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CD106 (VCAM-1) Rat anti-Mouse, Clone: 429, eBioscience™

Rat Monoclonal Antibody

$85.55 - $317.55

Specifications

Antigen CD106 (VCAM-1)
Clone 429
Host Species Rat
Gene Alias VCAM1, vascular cell adhesion molecule-1
Species Reactivity Mouse
View More Specs

 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

5012805

 
affymetrix
14-1061-81
50μg Each for $85.55

5012806

 
affymetrix
14-1061-82
100μg Each for $143.55

5012807

 
affymetrix
14-1061-85
500μg Each for $317.55
Description & Specifications

Specifications

Antigen CD106 (VCAM-1)
Clone 429
Host Species Rat
Gene Alias VCAM1, vascular cell adhesion molecule-1
Species Reactivity Mouse
Applications Flow Cytometry
Applications Functional Assay
Applications Immunohistochemistry (Frozen)
Applications Immunoprecipitation
Regulatory Status RUO
Conjugate Unlabeled
Format Purified
Storage Requirements Store at 2-8°C.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 0.5mg/mL

The 429 monoclonal antibody reacts with mouse CD106 (Vascular Cell Adhesion Molecule-1, VCAM-1), a 110kDa transmembrane glycoprotein expressed by myeloid lineage and bone marrow stromal cells. Endothelial cells constitutively express low levels of CD106 and upregulate it upon cytokine stimulation. CD106 binds to integrin α4β1 (VLA-4, CD49d/CD29) and Integrin a4b7 (LPAM-1) and these interactions in the bone marrow and thymus are important for early lymphocyte and myeloid development. Cytokine-mediated upregulation of CD106 on endothelial cells suggests a role for this antigen in the inflammatory response.