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CD106 (VCAM-1) Mouse anti-Rat, Clone: eBioMR106 (MR106), eBioscience™

Mouse Monoclonal Antibody

$129.05 - $361.05

Specifications

Antigen CD106 (VCAM-1)
Clone eBioMR106 (MR106)
Host Species Mouse
Gene Alias VCAM1, vascular cell adhesion molecule-1
Species Reactivity Rat
View More Specs

 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

5012802

 
affymetrix
14-1060-81
50μg Each for $129.05

5012803

 
affymetrix
14-1060-82
100μg Each for $216.05

5012804

 
affymetrix
14-1060-85
500μg Each for $361.05
Description & Specifications

Specifications

Antigen CD106 (VCAM-1)
Clone eBioMR106 (MR106)
Host Species Mouse
Gene Alias VCAM1, vascular cell adhesion molecule-1
Species Reactivity Rat
Applications Flow Cytometry
Applications Immunohistochemistry (Frozen)
Applications Immunoprecipitation
Applications Western Blotting
Regulatory Status RUO
Conjugate Unlabeled
Format Purified
Storage Requirements Store at 2-8°C.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 0.5mg/mL

The eBioMR106 monoclonal antibody reacts with rat CD106 (Vascular Cell Adhesion Molecule-1, VCAM-1), a 110kDa transmembrane glycoprotein expressed by myeloid lineage and bone marrow stromal cells. Endothelial cells constitutively express low levels of CD106 and further upregulate VCAM-1 upon cytokine stimulation. CD106 binds to integrin α4β1 (VLA-4, CD49d/CD29) and Integrin α4β7 (LPAM-1) and these interactions in the bone marrow and thymus are important for early lymphocyte and myeloid development. Cytokine-mediated upregulation of CD106 on endothelial cells suggests a role for this antigen in the inflammatory response.