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CD106 (VCAM-1) Mouse anti-Rat, Biotin, Clone: eBioMR106 (MR106), eBioscience™

Mouse Monoclonal Antibody

$143.55 - $230.55

Specifications

Antigen CD106 (VCAM-1)
Clone eBioMR106 (MR106)
Host Species Mouse
Gene Alias VCAM1, vascular cell adhesion molecule-1
Species Reactivity Rat
View More Specs

 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

5011694

 
affymetrix
13106081
50μg Each for $143.55

5011695

 
affymetrix
13-1060-82
100μg Each for $230.55
Description & Specifications

Specifications

Antigen CD106 (VCAM-1)
Clone eBioMR106 (MR106)
Host Species Mouse
Gene Alias VCAM1, vascular cell adhesion molecule-1
Species Reactivity Rat
Applications Flow Cytometry
Regulatory Status RUO
Conjugate Biotin
Format Conjugated
Storage Requirements Store at 2-8°C. Do not freeze.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 0.5mg/mL

The eBioMR106 monoclonal antibody reacts with rat CD106 (Vascular Cell Adhesion Molecule-1, VCAM-1), a 110kDa transmembrane glycoprotein expressed by myeloid lineage and bone marrow stromal cells. Endothelial cells constitutively express low levels of CD106 and further upregulate VCAM-1 upon cytokine stimulation. CD106 binds to integrin α4β1 (VLA-4, CD49d/CD29) and Integrin α4β7 (LPAM-1) and these interactions in the bone marrow and thymus are important for early lymphocyte and myeloid development. Cytokine-mediated upregulation of CD106 on endothelial cells suggests a role for this antigen in the inflammatory response.