Thermo Scientific™ Lab Vision™ CD105/Endoglin/TGF-β 1/3 Receptor Ab-3, Mouse Monoclonal Antibody
Ensure accurate, reproducible results in immunohistochemistry, western blotting and flow cytometry applications.
Manufacturer: Thermo Scientific™ Lab Vision™ MS1290PABX
Ensure accurate, reproducible results in immunohistochemistry, western blotting and flow cytometry applications with Thermo Scientific™ CD105/Endoglin/TGF-β1/3 Receptor Ab-3, Mouse Monoclonal Antibody.
CD105 or Endoglin or GP160 is a Type I transmembrane protein, which is highly expressed on human vascular endothelial cells. It exists as an O- and N-glycosylated homodimer. Up-regulation of endoglin expression has been demonstrated in tumor vasculature and proliferating cells, suggesting that it is a proliferation-associated endothelial cell marker. CD105 binds to TGF-Beta1 and Beta3 with high affinity but not TGF-Beta2.
Host Species: Mouse
Species Reactivity: Human. Others not tested.
Epitope: Not determined
Immunogen: Purified GP160 from cell membrane glycoproteins of fresh non-T/non-B acute lymphoblastic leukemia cells.
Molecular Weight: 95 kDa (monomer) and 190kDa (dimer)
Positive Control: HUVEC cells, Tonsil, lymph node and thymus
Cellular Localization: Membrane
- Immunohistochemistry (Formalin/paraffin)
- Western Blotting
- Flow Cytometry
USA: RUO; Int'l: RUO
|CD105/Endoglin/TGF-beta1/3 Receptor Ab-3|
|Ab without BSA/Azide (Frozen)|
|Flow Cytometry,Immunohistochemistry (Paraffin),Western Blotting|
|Purified GP160 from cell membrane glycoproteins of fresh non-T/non-B acute lymphoblastic leukemia cells|