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Thermo Scientific™ Lab Vision™ CD105/Endoglin/TGF-β 1/3 Receptor Ab-3, Mouse Monoclonal Antibody


Ensure accurate, reproducible results in immunohistochemistry, western blotting and flow cytometry applications.

Manufacturer: thermo scientific™ lab vision™  MS1290P1ABX

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Catalog No. MS1290P1ABX

  • / Each
 

Description & Specifications

Specifications

Antigen CD105/Endoglin/TGF-beta1/3 Receptor Ab-3
Applications Flow Cytometry
Applications Immunohistochemistry (Paraffin)
Applications Western Blotting
Classification Monoclonal
Clone SN6h
Concentration 1mg/mL
Conjugate Unlabeled
Cross Reactivity Human
Format Concentrated
Formulation Ab without BSA/Azide (Frozen)
Host Species Mouse
Immunogen Purified GP160 from cell membrane glycoproteins of fresh non-T/non-B acute lymphoblastic leukemia cells
Isotype IgG2a kappa
Quantity 100µL
Regulatory Status RUO
Research Discipline Angiogenesis
Type Primary

Ensure accurate, reproducible results in immunohistochemistry, western blotting and flow cytometry applications with Thermo Scientific™ CD105/Endoglin/TGF-β1/3 Receptor Ab-3, Mouse Monoclonal Antibody.

CD105 or Endoglin or GP160 is a Type I transmembrane protein, which is highly expressed on human vascular endothelial cells. It exists as an O- and N-glycosylated homodimer. Up-regulation of endoglin expression has been demonstrated in tumor vasculature and proliferating cells, suggesting that it is a proliferation-associated endothelial cell marker. CD105 binds to TGF-Beta1 and Beta3 with high affinity but not TGF-Beta2.

Host Species: Mouse

Clone: SN6h

Isotype: IgG1/κ

Species Reactivity: Human. Others not tested.

Epitope: Not determined

Immunogen: Purified GP160 from cell membrane glycoproteins of fresh non-T/non-B acute lymphoblastic leukemia cells.

Molecular Weight: 95 kDa (monomer) and 190kDa (dimer)

Positive Control: HUVEC cells, Tonsil, lymph node and thymus

Cellular Localization: Membrane

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting
  • Flow Cytometry

Note:

USA: RUO; Int'l: RUO