Please login to your online account to display your discounted pricing

CD100 (SEMA4D) Mouse anti-Human, Clone: eBio133-1C6 (133-1C6), eBioscience™

Mouse Monoclonal Antibody

$172.55 - $404.55

Specifications

Antigen CD100 (SEMA4D)
Clone eBio133-1C6 (133-1C6)
Host Species Mouse
Gene Alias Semaphorin 4D
Species Reactivity Human
View More Specs

 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

5012780

 
affymetrix
14-1009-80
25μg Each for $172.55

5012781

 
affymetrix
14-1009-82
100μg Each for $404.55
Description & Specifications

Specifications

Antigen CD100 (SEMA4D)
Clone eBio133-1C6 (133-1C6)
Host Species Mouse
Gene Alias Semaphorin 4D
Species Reactivity Human
Applications ELISA Capture
Applications Flow Cytometry
Applications Immunoprecipitation
Regulatory Status RUO
Conjugate Unlabeled
Format Purified
Storage Requirements Store at 2-8°C.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 0.5mg/mL

The eBio133-1C6 monoclonal antibody reacts with human CD100, a member of the class IV semaphorin family also called sema4D. CD100 promotes angiogenesis, invasive growth, proliferation, and anti-apoptosis of cancer cells in vitro. Furthermore CD100 is a costimulatory molecule in adaptive immune responses by switching off negative signalling from CD72. In addition to CD72 another ligand is Plexin-B1. It has been shown that higher expression levels of CD100 are correlated with poor survival in soft tissue sarcoma patients. Expression is found in both hematopoietic and non-hematopoietic cells.CD100 is expressed on resting T cells and NK cells and B cell. CD100 can also exist as a soluble form.