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CD100 (SEMA4D) Mouse anti-Human, Alexa Fluor 488, Clone: 133-1C6, eBioscience™

Mouse Monoclonal Antibody

$216.05 - $433.55

Specifications

Antigen CD100 (SEMA4D)
Clone eBio133-1C6 (133-1C6)
Host Species Mouse
Gene Alias Semaphorin 4D
Species Reactivity Human
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 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

5016712

 
affymetrix
53-1009-41
25 tests Each for $216.05

5016713

 
affymetrix
53-1009-42
100 tests Each for $433.55
Description & Specifications

Specifications

Antigen CD100 (SEMA4D)
Clone eBio133-1C6 (133-1C6)
Host Species Mouse
Gene Alias Semaphorin 4D
Species Reactivity Human
Applications Flow Cytometry
Regulatory Status RUO
Conjugate Alexa Fluor 488
Format Conjugated
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 5μL (0.25μg)/test

The eBio133-1C6 monoclonal antibody reacts with human CD100, a member of the class IV semaphorin family also called sema4D. CD100 promotes angiogenesis, invasive growth, proliferation, and anti-apoptosis of cancer cells in vitro. Furthermore CD100 is a costimulatory molecule in adaptive immune responses by switching off negative signalling from CD72. In addition to CD72 another ligand is Plexin-B1. It has been shown that higher expression levels of CD100 are correlated with poor survival in soft tissue sarcoma patients. Expression is found in both hematopoietic and non-hematopoietic cells.CD100 is expressed on resting T cells and NK cells and B cell. CD100 can also exist as a soluble form.