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CD100 (SEMA4D) Mouse anti-Human, Alexa Fluor 488, Clone: 133-1C6, eBioscience™

Mouse Monoclonal Antibody

$216.05 - $433.55

Specifications

Antigen CD100 (SEMA4D)
Clone eBio133-1C6 (133-1C6)
Host Species Mouse
Gene Alias Semaphorin 4D
Species Reactivity Human
View More Specs

 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

5016712

 
affymetrix
53100941
25 tests Each for $216.05

5016713

 
affymetrix
53100942
100 tests Each for $433.55
Description & Specifications

Specifications

Antigen CD100 (SEMA4D)
Clone eBio133-1C6 (133-1C6)
Host Species Mouse
Gene Alias Semaphorin 4D
Species Reactivity Human
Applications Flow Cytometry
Regulatory Status RUO
Conjugate Alexa Fluor 488
Format Conjugated
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 5μL (0.25μg)/test

The eBio133-1C6 monoclonal antibody reacts with human CD100, a member of the class IV semaphorin family also called sema4D. CD100 promotes angiogenesis, invasive growth, proliferation, and anti-apoptosis of cancer cells in vitro. Furthermore CD100 is a costimulatory molecule in adaptive immune responses by switching off negative signalling from CD72. In addition to CD72 another ligand is Plexin-B1. It has been shown that higher expression levels of CD100 are correlated with poor survival in soft tissue sarcoma patients. Expression is found in both hematopoietic and non-hematopoietic cells.CD100 is expressed on resting T cells and NK cells and B cell. CD100 can also exist as a soluble form.