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CD10 Mouse anti-Human, PerCP-eFluor 710, Clone: SN5c, eBioscience™

Mouse Monoclonal Antibody

$520.55 - $520.55

Specifications

Antigen CD10
Clone SN5c
Host Species Mouse
Gene Alias Common Acute Lymphocytic Leukemia antigen (CALLA), Neprilysin
Species Reactivity Human
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 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

5015914

 
affymetrix
46-0108-42
100 tests Each for $520.55
Description & Specifications

Specifications

Antigen CD10
Clone SN5c
Host Species Mouse
Gene Alias Common Acute Lymphocytic Leukemia antigen (CALLA), Neprilysin
Species Reactivity Human
Applications Flow Cytometry
Regulatory Status RUO
Conjugate PerCP-eFluor 710
Format Conjugated
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 5μL (0.25μg)/test

The eBioSN5c monoclonal antibody recognizes human CD10 (CALLA, NEP, enkephalinase, Neprilysin), which is a 100 kDa, type II cell surface glycoprotein originally identified for its expression on most acute lymphoblastic leukemias (ALLs). Subsequently, CD10 was shown to be the same molecule as neutral endopeptidase (NEP), or KII-NA. CD10 is a Zn2+-dependent metallopeptidase acting on substrates such as endothelin, glucagon, gastrin, neurotensin and bradykinin. CD10 is involved in the regulation of chemotactic and inflammatory processes involving neutrophils. In B cells, CD10 regulates stromal cell-dependent B lymphopoiesis and its expression has been reported on mature germinal center B cells. CD10 expression is also found on normal donor granulocytes and bone marrow stromal cells. Most likely, CB-CALLA and eBioSN5c see different epitopes due to their ability to co-stain.