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CD10 Mouse anti-Human, Biotin, Clone: SN5c, eBioscience™

Mouse Monoclonal Antibody

$100.05 - $216.05

Specifications

Antigen CD10
Clone SN5c
Host Species Mouse
Gene Alias Common Acute Lymphocytic Leukemia antigen (CALLA), Neprilysin,
Species Reactivity Human
View More Specs

 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

5011422

 
affymetrix
13-0108-80
25μg Each for $100.05

5011423

 
affymetrix
13010882
100μg Each for $216.05
Description & Specifications

Specifications

Antigen CD10
Clone SN5c
Host Species Mouse
Gene Alias Common Acute Lymphocytic Leukemia antigen (CALLA), Neprilysin,
Species Reactivity Human
Applications Flow Cytometry
Applications Immunohistochemistry (Frozen)
Regulatory Status RUO
Conjugate Biotin
Format Conjugated
Storage Requirements Store at 2-8°C. Do not freeze.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 0.5mg/mL

The eBioSN5c monoclonal antibody recognizes human CD10 (CALLA, NEP, enkephalinase, Neprilysin), which is a 100 kDa, type II cell surface glycoprotein originally identified for its expression on most acute lymphoblastic leukemias (ALLs). Subsequently, CD10 was shown to be the same molecule as neutral endopeptidase (NEP), or KII-NA. CD10 is a Zn2+-dependent metallopeptidase acting on substrates such as endothelin, glucagon, gastrin, neurotensin and bradykinin. CD10 is involved in the regulation of chemotactic and inflammatory processes involving neutrophils. In B cells, CD10 regulates stromal cell-dependent B lymphopoiesis and its expression has been reported on mature germinal center B cells. CD10 expression is also found on normal donor granulocytes and bone marrow stromal cells. Most likely, CB-CALLA and eBioSN5c see different epitopes due to their ability to co-stain.