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CD10 Mouse anti-Human, Biotin, Clone: SN5c, eBioscience™

Mouse Monoclonal Antibody

$91.08 - $196.68

Specifications

Antigen CD10
Clone SN5c
Host Species Murine
Gene Alias Common Acute Lymphocytic Leukemia antigen (CALLA), Neprilysin,
Species Reactivity Human
View More Specs

Disclaimers:

For Research Use Only.



Products ${productFamilyLength}
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
5011422 Life Technologies
LS13010880
25μg Each for $91.08
5011423 Life Technologies
LS13010882
100μg Each for $196.68
Specifications

Description

The eBioSN5c monoclonal antibody recognizes human CD10 (CALLA, NEP, enkephalinase, Neprilysin), which is a 100 kDa, type II cell surface glycoprotein originally identified for its expression on most acute lymphoblastic leukemias (ALLs). Subsequently, CD10 was shown to be the same molecule as neutral endopeptidase (NEP), or KII-NA. CD10 is a Zn2+-dependent metallopeptidase acting on substrates such as endothelin, glucagon, gastrin, neurotensin and bradykinin. CD10 is involved in the regulation of chemotactic and inflammatory processes involving neutrophils. In B cells, CD10 regulates stromal cell-dependent B lymphopoiesis and its expression has been reported on mature germinal center B cells. CD10 expression is also found on normal donor granulocytes and bone marrow stromal cells. Most likely, CB-CALLA and eBioSN5c see different epitopes due to their ability to co-stain.
Description & Specifications

Specifications

CD10
Murine
Human
RUO
Conjugated
Primary
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
SN5c
Common Acute Lymphocytic Leukemia antigen (CALLA), Neprilysin,
Flow Cytometry,Immunohistochemistry (Frozen)
Biotin
Store at 2-8°C. Do not freeze.
Monoclonal
0.5mg/mL