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CD10 Mouse anti-Human, Biotin, Clone: eBioCB-CALLA (CB-CALLA), eBioscience™

Mouse Monoclonal Antibody

$100.05 - $216.05

Specifications

Antigen CD10
Clone eBioCB-CALLA (CB-CALLA)
Host Species Mouse
Gene Alias Common Acute Lymphocytic Leukemia antigen (CALLA), Neprilysin
Species Reactivity Human
View More Specs

 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

5011420

 
affymetrix
13010680
25μg Each for $100.05

5011421

 
affymetrix
13010682
100μg Each for $216.05
Description & Specifications

Specifications

Antigen CD10
Clone eBioCB-CALLA (CB-CALLA)
Host Species Mouse
Gene Alias Common Acute Lymphocytic Leukemia antigen (CALLA), Neprilysin
Species Reactivity Human
Applications Flow Cytometry
Regulatory Status RUO
Conjugate Biotin
Format Conjugated
Storage Requirements Store at 2-8°C. Do not freeze.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 0.5mg/mL

The eBioCB-CALLA monoclonal antibody recognizes human CD10 (CALLA, NEP, enkephalinase, Neprilysin), which is a 100 kDa, type II cell surface glycoprotein originally identified for its expression on most acute lymphoblastic leukemias (ALL). Subsequently, CD10 was shown to be the same molecule as the neutral endopeptidase (NEP), or KII-NA. CD10 is a Zn2+-dependent metallo-peptidase with endothelin, glucagon, gastrin, neurotensin and bradykinin included among its substrates. CD10 is involved in the regulation of chemotactic and inflammatory processes involving neutrophils. In B cells, CD10 regulates stromal cell-dependent B lymphopoiesis and expression has also been reported on mature B cells in germinal centres. In addition to the hematopoietic compartment, other major sites of CD10 expression are the brush border of enterocytes and renal tubules and glomeruli. There is partial blocking of the eBioCB-CALLA and MEM-78 monoclonal antibodies indicating that they recognize similar epitopes.