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CD10 Mouse anti-Human, Alexa Fluor 700, Clone: CB-CALLA, eBioscience™

Mouse Monoclonal Antibody

$170.28 - $381.48

Specifications

Antigen CD10
Clone eBioCB-CALLA (CB-CALLA)
Host Species Murine
Gene Alias Common Acute Lymphocytic Leukemia antigen (CALLA), Neprilysin
Species Reactivity Human
View More Specs

Disclaimers:

For Research Use Only.



Products ${productFamilyLength}
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
501124671 Life Technologies
LS56010641
25 Tests Each for $170.28
501124672 Life Technologies
LS56010642
100 Tests Each for $381.48
Specifications

Description

The eBioCB-CALLA monoclonal antibody recognizes human CD10 (CALLA, NEP, enkephalinase, Neprilysin), which is a 100 kDa, type II cell surface glycoprotein originally identified for its expression on most acute lymphoblastic leukemias (ALL). Subsequently, CD10 was shown to be the same molecule as the neutral endopeptidase (NEP), or KII-NA. CD10 is a Zn2+-dependent metallo-peptidase with endothelin, glucagon, gastrin, neurotensin and bradykinin included among its substrates. CD10 is involved in the regulation of chemotactic and inflammatory processes involving neutrophils. In B cells, CD10 regulates stromal cell-dependent B lymphopoiesis and expression has also been reported on mature B cells in germinal centres. In addition to the hematopoietic compartment, other major sites of CD10 expression are the brush border of enterocytes and renal tubules and glomeruli. There is partial blocking of the eBioCB-CALLA and MEM-78 monoclonal antibodies indicating that they recognize similar epitopes.
Description & Specifications

Specifications

CD10
Murine
Human
RUO
Conjugated
Primary
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
eBioCB-CALLA (CB-CALLA)
Common Acute Lymphocytic Leukemia antigen (CALLA), Neprilysin
Flow Cytometry
Alexa Fluor 700
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
5μL (0.25μg)/test