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Thermo Scientific™ Lab Vision™ Caspase 9/LAP6 Ab-4, Rabbit Polyclonal Antibody

Obtain accurate, reproducible results in immunohistochemistry, western blotting, and immunoprecipitation experiments.

$227.78 - $1,510.63

Specifications

Antigen Caspase 9/LAP6 Ab-4
Concentration 1mg/mL
Applications Immunoprecipitation
Applications Western Blotting
Applications Immunoprecipitation
View More Specs
Products
Catalog Number Mfr. No. Formulation Quantity Price Quantity    

RB1205B

 
thermo scientific™ lab vision™
RB-1205-B
Biotinylated Ab with BSA and Azide 1mL Each for $1,510.63

RB1205B0

 
thermo scientific™ lab vision™
RB-1205-B0
Biotinylated Ab with BSA and Azide 100µL Each for $313.65

RB1205B1

 
thermo scientific™ lab vision™
RB-1205-B1
Biotinylated Ab with BSA and Azide 500µL Each for $942.43

RB1205P

 
thermo scientific™ lab vision™
RB-1205-P
Purified Ab with BSA and Azide 1mL Each for $1,196.92

RB1205P0

 
thermo scientific™ lab vision™
RB-1205-P0
Purified Ab with BSA and Azide 100µL Each for $227.78

RB1205P1

 
thermo scientific™ lab vision™
RB-1205-P1
Purified Ab with BSA and Azide 500µL Each for $724.29

RB1205P1ABX

 
thermo scientific™ lab vision™
RB1205P1ABX
Ab without BSA/Azide (Frozen) 500µL Each for $791.67

RB1205PABX

 
thermo scientific™ lab vision™
RB1205PABX
Ab without BSA/Azide (Frozen) 1mL Each for $1,315.61
Description & Specifications

Specifications

Antigen Caspase 9/LAP6 Ab-4
Concentration 1mg/mL
Applications Immunoprecipitation
Applications Western Blotting
Applications Immunoprecipitation
Applications Western Blotting
Classification Polyclonal
Cross Reactivity Bovine
Cross Reactivity Human
Cross Reactivity Mouse
Cross Reactivity Rat
Cross Reactivity Bovine
Cross Reactivity Human
Cross Reactivity Mouse
Cross Reactivity Rat
Cross Reactivity Bovine
Cross Reactivity Human
Cross Reactivity Mouse
Cross Reactivity Rat
Cross Reactivity Bovine
Cross Reactivity Human
Cross Reactivity Mouse
Cross Reactivity Rat
Format Concentrated
Host Species Rabbit
Regulatory Status RUO
Research Discipline Apoptosis
Type Primary
Immunogen Recombinant protein encoding aa 1-134 of human caspase 9
Isotype IgG

Obtain accurate, reproducible results in immunohistochemistry, western blotting and immunoprecipitation experiments with Thermo Scientific™ Caspase 9/LAP6 Ab-4, Rabbit Polyclonal Antibody. 

 

Activation of procaspase-9 by Apaf-1 in the cytochrome c/dATP-dependent pathway requires proteolytic cleavage to generate the mature caspase molecule. Deletion of the Apaf-1 WD-40 repeats makes Apaf-1 constitutively active and capable of processing procaspase-9 independent of cytochrome c and ATP. Apaf-1-mediated processing of procaspase-9 occurs at Asp-315 by an intrinsic autocatalytic activity of procaspase-9 itself. Apaf-1 can form oligomers and may facilitate procaspase-9 autoactivation by oligomerizing its precursor molecules. Once activated, caspase-9 can initiate a caspase cascade involving the downstream executioners caspase-3, -6, and -7.

Host Species: Rabbit

Isotype: IgG

Species Reactivity: Human, Mouse, Rat, Cow and Sheep. Others not tested.

Epitope: aa 1-134

Immunogen: Recombinant protein encoding aa 1-134 of human caspase 9

Molecular Weight: 46-48 kDa

Positive Control: Jurkat cells, Tonsil

Cellular Localization: Cytoplasmic

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting
  • Immunoprecipitation (Denatured verified)

Note:

USA: RUO; Int'l: RUO