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Thermo Scientific™ Lab Vision™ Caspase 9/LAP6 Ab-4, Rabbit Polyclonal Antibody

Obtain accurate, reproducible results in immunohistochemistry, western blotting, and immunoprecipitation experiments.

$244.88 - $1,624.20

Specifications

Antigen Caspase 9/LAP6 Ab-4
Concentration 1mg/mL
Applications Immunoprecipitation,Western Blotting,Immunoprecipitation,Western Blotting
Classification Polyclonal
Format Concentrated
View More Specs


Products ${productFamilyLength}
Catalog Number Mfr. No. Formulation Quantity Price Quantity  
Catalog Number Mfr. No. Formulation Quantity Price Quantity  
RB1205B Thermo Scientific™ Lab Vision™
RB1205B
Biotinylated Ab with BSA and Azide 1mL Each for $1,624.20
RB1205B0 Thermo Scientific™ Lab Vision™
RB1205B0
Biotinylated Ab with BSA and Azide 100μL Each for $337.41
RB1205B1 Thermo Scientific™ Lab Vision™
RB1205B1
Biotinylated Ab with BSA and Azide 500μL Each for $1,013.37
RB1205P Thermo Scientific™ Lab Vision™
RB1205P
Purified Ab with BSA and Azide 1mL Each for $1,286.90
RB1205P0 Thermo Scientific™ Lab Vision™
RB1205P0
Purified Ab with BSA and Azide 100μL Each for $244.88
RB1205P1 Thermo Scientific™ Lab Vision™
RB1205P1
Purified Ab with BSA and Azide 500μL Each for $778.82
RB1205P1ABX Thermo Scientific™ Lab Vision™
RB1205P1ABX
Ab without BSA/Azide (Frozen) 500μL Each for $851.35
RB1205PABX Thermo Scientific™ Lab Vision™
RB1205PABX
Ab without BSA/Azide (Frozen) 1mL Each for $1,414.65
Specifications

Description

Obtain accurate, reproducible results in immunohistochemistry, western blotting and immunoprecipitation experiments with Thermo Scientific™ Caspase 9/LAP6 Ab-4, Rabbit Polyclonal Antibody. 

 

Activation of procaspase-9 by Apaf-1 in the cytochrome c/dATP-dependent pathway requires proteolytic cleavage to generate the mature caspase molecule. Deletion of the Apaf-1 WD-40 repeats makes Apaf-1 constitutively active and capable of processing procaspase-9 independent of cytochrome c and ATP. Apaf-1-mediated processing of procaspase-9 occurs at Asp-315 by an intrinsic autocatalytic activity of procaspase-9 itself. Apaf-1 can form oligomers and may facilitate procaspase-9 autoactivation by oligomerizing its precursor molecules. Once activated, caspase-9 can initiate a caspase cascade involving the downstream executioners caspase-3, -6, and -7.

Host Species: Rabbit

Isotype: IgG

Species Reactivity: Human, Mouse, Rat, Cow and Sheep. Others not tested.

Epitope: aa 1-134

Immunogen: Recombinant protein encoding aa 1-134 of human caspase 9

Molecular Weight: 46-48 kDa

Positive Control: Jurkat cells, Tonsil

Cellular Localization: Cytoplasmic

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting
  • Immunoprecipitation (Denatured verified)

Note:

USA: RUO; Int'l: RUO

Description & Specifications

Specifications

Caspase 9/LAP6 Ab-4
Immunoprecipitation,Western Blotting,Immunoprecipitation,Western Blotting
Concentrated
RUO
Primary
IgG
1mg/mL
Polyclonal
Rabbit
Apoptosis
Recombinant protein encoding aa 1-134 of human caspase 9