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Thermo Scientific™ Lab Vision™ Caspase 9/LAP6 Ab-4, Rabbit Polyclonal Antibody

Obtain accurate, reproducible results in immunohistochemistry, western blotting, and immunoprecipitation experiments.

Manufacturer: thermo scientific™ lab vision™  RB1205P1ABX

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Catalog No. RB1205P1ABX


Description & Specifications


Antigen Caspase 9/LAP6 Ab-4
Applications Immunoprecipitation
Applications Western Blotting
Classification Polyclonal
Concentration 1mg/mL
Conjugate Unlabeled
Cross Reactivity Bovine
Cross Reactivity Human
Cross Reactivity Mouse
Cross Reactivity Rat
Format Concentrated
Formulation Ab without BSA/Azide (Frozen)
Host Species Rabbit
Immunogen Recombinant protein encoding aa 1-134 of human caspase 9
Isotype IgG
Quantity 500µL
Regulatory Status RUO
Research Discipline Apoptosis
Type Primary

Obtain accurate, reproducible results in immunohistochemistry, western blotting and immunoprecipitation experiments with Thermo Scientific™ Caspase 9/LAP6 Ab-4, Rabbit Polyclonal Antibody. 


Activation of procaspase-9 by Apaf-1 in the cytochrome c/dATP-dependent pathway requires proteolytic cleavage to generate the mature caspase molecule. Deletion of the Apaf-1 WD-40 repeats makes Apaf-1 constitutively active and capable of processing procaspase-9 independent of cytochrome c and ATP. Apaf-1-mediated processing of procaspase-9 occurs at Asp-315 by an intrinsic autocatalytic activity of procaspase-9 itself. Apaf-1 can form oligomers and may facilitate procaspase-9 autoactivation by oligomerizing its precursor molecules. Once activated, caspase-9 can initiate a caspase cascade involving the downstream executioners caspase-3, -6, and -7.

Host Species: Rabbit

Isotype: IgG

Species Reactivity: Human, Mouse, Rat, Cow and Sheep. Others not tested.

Epitope: aa 1-134

Immunogen: Recombinant protein encoding aa 1-134 of human caspase 9

Molecular Weight: 46-48 kDa

Positive Control: Jurkat cells, Tonsil

Cellular Localization: Cytoplasmic

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting
  • Immunoprecipitation (Denatured verified)


USA: RUO; Int'l: RUO