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Thermo Scientific™ Lab Vision™ Caspase 6 (Mch 2) Ab-3, Mouse Monoclonal Antibody

Ensure accurate, reproducible results in western blotting and immunoprecipitation procedures with Thermo Scientific™ Caspase 6 (Mch 2) Ab-3, Mouse Monoclonal Antibody.

Manufacturer:  Thermo Scientific™ Lab Vision™ MS1126PABX

 View more versions of this product

Catalog No. MS1126PABX


 

Specifications

Description

Ensure accurate, reproducible results in western blotting and immunoprecipitation procedures with Thermo Scientific™ Caspase 6 (Mch 2) Ab-3, Mouse Monoclonal Antibody.

Caspases play a major role in the transduction of the apoptotic signal and execution of apoptosis in mammalian cells. Caspase 3 (CPP32) and Caspase 6 (Mch2) are the major active caspases in apoptotic cells, and are activated in response to distinct apoptosis-inducing stimuli in all cell lines analyzed. Both CPP32 and Mch2 are present in apoptotic cells as multiple active species. Caspase-6 cleaves nuclear mitotic apparatus protein (NuMA) and mediates the shrinkage and fragmentation of nuclei.

Host Species: Mouse

Clone: 6CSP03; same as 14.1.190

Isotype: IgG1/κ

Species Reactivity: Human. Others not tested.

Epitope: Caspase 6 prodomain

Immunogen: Recombinant human caspase 6 prodomain

Molecular Weight: 34 kDa

Positive Control: Jurkat cells

Cellular Localization: Cytoplasmic

Recommended for:

  • Western Blotting
  • Immunoprecipitation

Note:

USA: RUO; Int'l: RUO

Description & Specifications

Specifications

Caspase 6 (Mch 2) Ab-3
Monoclonal
1mg/mL
Human
Murine
IgG2a kappa
RUO
Primary
Human
Immunoprecipitation,Western Blotting
6CSP03; same as 14.1.190
Unlabeled
Concentrated
Recombinant human caspase 6 prodomain
200μL
Apoptosis
Monoclonal