Thermo Scientific™ Lab Vision™ Caspase 3 (CPP32) Ab-4, Rabbit Polyclonal Antibody
Ensure accurate, reproducible results in immunohistochemistry, western blotting and immunoprecipitation procedures.
Manufacturer: Thermo Scientific™ Lab Vision™ RB1197PABX
Ensure accurate, reproducible results in immunohistochemistry, western blotting and immunoprecipitation procedures with Thermo Scientific™ Caspase 3 (CPP32) Ab-4, Rabbit Polyclonal Antibody.Caspase 3 is ubiquitously expressed and like other caspases is synthesized as an inactive (32 kDa) proenzyme. Upon activation, Caspase 3 is cleaved at Asp28-Ser29 and Asp175-Ser176 thereby generating two subunits of 17 kDa and 12 kDa, respectively. Recent studies have implicated that Caspase 3 is associated with the induction of apoptosis. Activation of Caspase 3 occurs in response to a variety of apoptotic inducers including Fas-mediated apoptosis.
Host Species: Rabbit
Species Reactivity: Human, Mouse, Rat, Monkey, Rabbit, Hamster, Cow, Sheep, Pig and Dog. Others not tested.
Epitope: Not determined
Immunogen: Recombinant full-length human caspase 3 protein
Molecular Weight: 32 kDa
Positive Control: Jurkat cells, Tonsil
Cellular Localization: Predominantly cytoplasmic with some nuclear staining
- Immunohistochemistry (Formalin/paraffin)
- Western Blotting
- Immunoprecipitation (Denatured verified)
USA: RUO; Int'l: RUO
|Caspase 3 (CPP32) Ab-4|
|Recombinant full length human caspase 3 protein|
|Ab without BSA/Azide (Frozen)|