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Thermo Scientific™ Lab Vision™ Caspase 3 (CPP32) Ab-4, Rabbit Polyclonal Antibody


Ensure accurate, reproducible results in immunohistochemistry, western blotting and immunoprecipitation procedures.

Manufacturer: thermo scientific™ lab vision™  RB1197P1ABX

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Catalog No. RB1197P1ABX

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Description & Specifications

Specifications

Antigen Caspase 3 (CPP32) Ab-4
Applications Immunoprecipitation
Applications Western Blotting
Classification Polyclonal
Concentration 1mg/mL
Conjugate Unlabeled
Cross Reactivity Bovine
Cross Reactivity Canine
Cross Reactivity Hamster
Cross Reactivity Human
Cross Reactivity Mouse
Cross Reactivity Non-Human Primate
Cross Reactivity Porcine
Cross Reactivity Rabbit
Cross Reactivity Rat
Format Concentrated
Formulation Ab without BSA/Azide (Frozen)
Host Species Rabbit
Immunogen Recombinant full length human caspase 3 protein
Isotype IgG
Quantity 500µL
Regulatory Status RUO
Research Discipline Apoptosis
Type Primary

Ensure accurate, reproducible results in immunohistochemistry, western blotting and immunoprecipitation procedures with Thermo Scientific™ Caspase 3 (CPP32) Ab-4, Rabbit Polyclonal Antibody.

Caspase 3 is ubiquitously expressed and like other caspases is synthesized as an inactive (32 kDa) proenzyme. Upon activation, Caspase 3 is cleaved at Asp28-Ser29 and Asp175-Ser176 thereby generating two subunits of 17 kDa and 12 kDa, respectively. Recent studies have implicated that Caspase 3 is associated with the induction of apoptosis. Activation of Caspase 3 occurs in response to a variety of apoptotic inducers including Fas-mediated apoptosis.

Host Species: Rabbit

Isotype: IgG

Species Reactivity: Human, Mouse, Rat, Monkey, Rabbit, Hamster, Cow, Sheep, Pig and Dog. Others not tested.

Epitope: Not determined

Immunogen: Recombinant full-length human caspase 3 protein

Molecular Weight: 32 kDa

Positive Control: Jurkat cells, Tonsil

Cellular Localization: Predominantly cytoplasmic with some nuclear staining

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting
  • Immunoprecipitation (Denatured verified)

Note:

USA: RUO; Int'l: RUO