Please login to your online account to display your discounted pricing

Thermo Scientific™ Lab Vision™ Caspase 3 (CPP32) Ab-4, Rabbit Polyclonal Antibody


Ensure accurate, reproducible results in immunohistochemistry, western blotting and immunoprecipitation procedures.

Manufacturer: thermo scientific™ lab vision™  RB1197P1ABX

 View more versions of this product

Catalog No. RB1197P1ABX

  • / Each
 

Description & Specifications

Specifications

Antigen Caspase 3 (CPP32) Ab-4
Applications Immunoprecipitation
Applications Western Blotting
Classification Polyclonal
Concentration 1mg/mL
Conjugate Unlabeled
Cross Reactivity Bovine
Cross Reactivity Canine
Cross Reactivity Hamster
Cross Reactivity Human
Cross Reactivity Mouse
Cross Reactivity Non-Human Primate
Cross Reactivity Porcine
Cross Reactivity Rabbit
Cross Reactivity Rat
Format Concentrated
Formulation Ab without BSA/Azide (Frozen)
Host Species Rabbit
Immunogen Recombinant full length human caspase 3 protein
Isotype IgG
Quantity 500μL
Regulatory Status RUO
Research Discipline Apoptosis
Type Primary
Monoclonal or Polyclonal Polyclonal
Target Species Bovine
Target Species Canine
Target Species Hamster
Target Species Human
Target Species Murine
Target Species Non-human Primate
Target Species Porcine
Target Species Rabbit
Target Species Rat

Ensure accurate, reproducible results in immunohistochemistry, western blotting and immunoprecipitation procedures with Thermo Scientific™ Caspase 3 (CPP32) Ab-4, Rabbit Polyclonal Antibody.

Caspase 3 is ubiquitously expressed and like other caspases is synthesized as an inactive (32 kDa) proenzyme. Upon activation, Caspase 3 is cleaved at Asp28-Ser29 and Asp175-Ser176 thereby generating two subunits of 17 kDa and 12 kDa, respectively. Recent studies have implicated that Caspase 3 is associated with the induction of apoptosis. Activation of Caspase 3 occurs in response to a variety of apoptotic inducers including Fas-mediated apoptosis.

Host Species: Rabbit

Isotype: IgG

Species Reactivity: Human, Mouse, Rat, Monkey, Rabbit, Hamster, Cow, Sheep, Pig and Dog. Others not tested.

Epitope: Not determined

Immunogen: Recombinant full-length human caspase 3 protein

Molecular Weight: 32 kDa

Positive Control: Jurkat cells, Tonsil

Cellular Localization: Predominantly cytoplasmic with some nuclear staining

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting
  • Immunoprecipitation (Denatured verified)

Note:

USA: RUO; Int'l: RUO