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Thermo Scientific™ Lab Vision™ Caspase 3 (CPP32) Ab-3, Mouse Monoclonal Antibody


Ensure accurate, reproducible results in immunohistochemistry, western blotting and immunoprecipitation procedures.

Manufacturer: thermo scientific™ lab vision™  MS1123PABX

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Catalog No. MS1123PABX

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Description & Specifications

Specifications

Antigen Caspase 3 (CPP32) Ab-3
Applications Immunohistochemistry (Paraffin)
Applications Immunoprecipitation
Applications Western Blotting
Classification Monoclonal
Clone 3CSP03; same as 4.1.18
Concentration 1mg/mL
Conjugate Unlabeled
Cross Reactivity Human
Format Concentrated
Formulation Ab without BSA/Azide (Frozen)
Host Species Murine
Immunogen Recombinant full length human Caspase 3 protein
Isotype IgG2a
Quantity 200μL
Regulatory Status RUO
Research Discipline Apoptosis
Type Primary
Monoclonal or Polyclonal Monoclonal
Target Species Human

Ensure accurate, reproducible results in immunohistochemistry, western blotting and immunoprecipitation procedures with Thermo Scientific™ Caspase 3 (CPP32) Ab-3, Mouse Monoclonal Antibody.

Caspase 3 is ubiquitously expressed and like other caspases is synthesized as an inactive (32kDa) proenzyme. Upon activation, Caspase 3 is cleaved at Asp28-Ser29 and Asp175-Ser176 thereby generating two subunits of 17kDa and 12kDa, respectively. Recent studies have implicated that Caspase 3 is associated with the induction of apoptosis. Activation of Caspase 3 occurs in response to a variety of apoptotic inducers including Fas-mediated apoptosis.

Host Species: Mouse

Clone: 3CSP03; same as 4.1.18

Isotype: IgG2a

Species Reactivity: Human. Others not tested.

Epitope: Not determined

Immunogen: Recombinant full-length human Caspase 3 protein

Molecular Weight: 32 kDa

Positive Control: Jurkat cells, Tonsil and appendix

Cellular Localization: Predominantly Cytoplasmic with some nuclear staining

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting
  • Immunoprecipitation (Native verified)

Note:

USA: RUO; Int'l: RUO