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Thermo Scientific™ Lab Vision™ Caspase 3 (CPP32) Ab-3, Mouse Monoclonal Antibody


Ensure accurate, reproducible results in immunohistochemistry, western blotting and immunoprecipitation procedures.

Manufacturer: thermo scientific™ lab vision™  MS1123PABX

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Catalog No. MS1123PABX

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Description & Specifications

Specifications

Antigen Caspase 3 (CPP32) Ab-3
Applications Immunohistochemistry (Paraffin)
Applications Immunoprecipitation
Applications Western Blotting
Classification Monoclonal
Clone 3CSP03; same as 4.1.18
Concentration 1mg/mL
Conjugate Unlabeled
Cross Reactivity Human
Format Concentrated
Formulation Ab without BSA/Azide (Frozen)
Host Species Mouse
Immunogen Recombinant full length human Caspase 3 protein
Isotype IgG2a
Quantity 200µL
Regulatory Status RUO
Research Discipline Apoptosis
Type Primary

Ensure accurate, reproducible results in immunohistochemistry, western blotting and immunoprecipitation procedures with Thermo Scientific™ Caspase 3 (CPP32) Ab-3, Mouse Monoclonal Antibody.

Caspase 3 is ubiquitously expressed and like other caspases is synthesized as an inactive (32kDa) proenzyme. Upon activation, Caspase 3 is cleaved at Asp28-Ser29 and Asp175-Ser176 thereby generating two subunits of 17kDa and 12kDa, respectively. Recent studies have implicated that Caspase 3 is associated with the induction of apoptosis. Activation of Caspase 3 occurs in response to a variety of apoptotic inducers including Fas-mediated apoptosis.

Host Species: Mouse

Clone: 3CSP03; same as 4.1.18

Isotype: IgG2a

Species Reactivity: Human. Others not tested.

Epitope: Not determined

Immunogen: Recombinant full-length human Caspase 3 protein

Molecular Weight: 32 kDa

Positive Control: Jurkat cells, Tonsil and appendix

Cellular Localization: Predominantly Cytoplasmic with some nuclear staining

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting
  • Immunoprecipitation (Native verified)

Note:

USA: RUO; Int'l: RUO