Thermo Scientific™ Lab Vision™ Caspase 3 (CPP32) Ab-1, Mouse Monoclonal Antibody
Ensure accurate, reproducible results in immunohistochemistry, western blotting and immunoprecipitation procedures.
Manufacturer: Thermo Scientific™ Lab Vision™ MS1121P1ABX
Ensure accurate, reproducible results in immunohistochemistry, western blotting and immunoprecipitation procedures with Thermo Scientific™ Caspase 3 (CPP32) Ab-1, Mouse Monoclonal Antibody.Caspase 3 is ubiquitously expressed and like other caspases is synthesized as an inactive (32 kDa) proenzyme. Upon activation, Caspase 3 is cleaved at Asp28-Ser29 and Asp175-Ser176 thereby generating two subunits of 17kDa and 12kDa, respectively. Recent studies have implicated that Caspase 3 is associated with the induction of apoptosis. Activation of Caspase 3 occurs in response to a variety of apoptotic inducers including Fas-mediated apoptosis.
Host Species: Mouse
Clone: 3CSP01; same as 7.1.44
Species Reactivity: Human. Others not tested.
Epitope: Not determined
Immunogen: Recombinant full-length human Caspase 3 protein
Molecular Weight: 32 kDa
Positive Control: Jurkat cells, Tonsil and appendix
Cellular Localization: Predominantly Cytoplasmic with some nuclear staining
- Immunohistochemistry (Formalin/paraffin)
- Western Blotting
- Immunoprecipitation (Native and denatured)
USA: RUO; Int'l: RUO
|Caspase 3 (CPP32) Ab-1|
|Ab without BSA/Azide (Frozen)|
|Immunohistochemistry (Paraffin),Immunoprecipitation,Western Blotting|
|3CSP01; same as 7.1.44|
|Recombinant full length human Caspase 3 protein|