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Caspase 1 Rat anti-Mouse, Clone: 5B10, eBioscience™

Rat Monoclonal Antibody

$129.05 - $288.55

Specifications

Antigen Caspase 1
Clone 5B10
Host Species Rat
Gene Alias Caspase1
Species Reactivity Mouse
View More Specs

 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

5013820

 
affymetrix
14983280
25μg Each for $129.05

5013821

 
affymetrix
14983282
100μg Each for $288.55
Description & Specifications

Specifications

Antigen Caspase 1
Clone 5B10
Host Species Rat
Gene Alias Caspase1
Species Reactivity Mouse
Applications Western Blotting
Regulatory Status RUO
Conjugate Unlabeled
Format Purified
Storage Requirements Store at 2-8°C.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 0.5mg/mL

The monoclonal antibody 5B10 recognizes mouse Caspase-1, a member of the cysteine-requiring aspartate protease family, which plays a critical role in cell suicide known as apoptosis. In particular, it converts pro-IL-1β to mature IL-1β; hence it is also called ICE (interleukin-1β converting enzyme). Upon activation Caspase-1 exists as a tetramer of two p20 and two p10 subunits. There are several isoforms of Caspase-1.

The 5B10 antibody recognizes both the pro-form of about 42kDa and the active p20 form.