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Thermo Scientific™ Lab Vision™ Cadherin-P Ab-1, Mouse Monoclonal Antibody

Obtain accurate, reproducible results in immunohistochemistry experiments with Thermo Scientific™ Cadherin-P Ab-1, Mouse Monoclonal Antibody.

$224.55 - $1,071.39

Specifications

Antigen Cadherin-P/P-cadherin Ab-1
Clone 56C1
Applications Immunohistochemistry (Paraffin)
Classification Monoclonal
Conjugate Unlabeled
View More Specs
Products
Catalog Number Mfr. No. Quantity Price Quantity    

MS1741R7

 
thermo scientific™ lab vision™
MS1741R7
7mL Each for $630.39

MS1741S

 
thermo scientific™ lab vision™
MS1741S
1mL Each for $1,071.39

MS1741S0

 
thermo scientific™ lab vision™
MS1741S0
100µL Each for $224.55

MS1741S1

 
thermo scientific™ lab vision™
MS1741S1
500µL Each for $748.76
Description & Specifications

Specifications

Antigen Cadherin-P/P-cadherin Ab-1
Clone 56C1
Applications Immunohistochemistry (Paraffin)
Classification Monoclonal
Conjugate Unlabeled
Host Species Mouse
Regulatory Status RUO
Research Discipline Junction Protein
Type Primary
Immunogen Recombinant protein corresponding to extracellular domain of human P-cadherin

Obtain accurate, reproducible results in immunohistochemistry experiments with Thermo Scientific™ Cadherin-P Ab-1, Mouse Monoclonal Antibody.

Cadherins are calcium dependent cell adhesion molecules, which play important roles in the growth and development of cells via the mechanisms of control of tissue architecture and the maintenance of tissue integrity. They are expressed in a tissue specific manner and are required for assembly of cells into solid tissue. Individual cadherin molecules are known to cooperate with each other to form a linear cell adhesion zipper. In adhesion junctions cadherins are bound to Beta and gamma catenins which in turn bind to alpha catenin, an actin binding protein. Cadherins play important part in tumor invasion and metastasis. P-cadherin is selectively expressed in basal and parabasal layers of stratified epithelia. It may be involved in the final stages of tumor progression in epidermal carcinoma. Changes in P-cadherin expression have been implicated in breast and melanocytic tumors.

Host Species: Mouse

Clone: 56C1

Isotype: IgG1

Species Reactivity: Human. Others not known.

Epitope: External domain

Immunogen: Recombinant protein corresponding to extracellular domain of human cadherin-P

Molecular Weight: 120kDa

Positive Control: Skin

Cellular Localization: Membrane

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)

Note:

USA: IVD; Int'l: IVD