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c-Myc Mouse anti-Human, Clone: 9E10, eBioscience™

Mouse Monoclonal Antibody

$129.05 - $274.05

Specifications

Antigen c-Myc
Clone 9.00E+10
Host Species Mouse
Gene Alias Myc proto-oncogene protein
Species Reactivity Human
View More Specs

 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

5013548

 
affymetrix
14-6784-80
25μg Each for $129.05

5013549

 
affymetrix
14-6784-82
100μg Each for $274.05
Description & Specifications

Specifications

Antigen c-Myc
Clone 9.00E+10
Host Species Mouse
Gene Alias Myc proto-oncogene protein
Species Reactivity Human
Applications Immunohistochemistry (Formalin/Paraffin)
Applications Immunoprecipitation
Applications Western Blotting
Regulatory Status RUO
Conjugate Unlabeled
Format Purified
Storage Requirements Store at 2-8°C.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 0.5mg/mL

The 9E10 antibody reacts with human c-Myc p67; the antibody was raised against a synthetic peptide corresponding to amino acids 408-439 within the carboxy terminal domain of human c-Myc. This antibody can be used to detect myc-tagged protein. The transcription factor c-Myc is a proto-oncogene that is at the focal point in cell cycle regulation, metabolism, apoptosis, differentiation, cell adhesion, and tumorigenesis. In normal cells the expression of c-Myc is tightly regulated but in human cancers c-Myc is frequently deregulated. C-Myc also plays a pivotal role in apoptosis, most notably its connections to the CD95/Fas death receptor pathway. These different biological responses to c-Myc are most likely the result of different overlapping subsets of c-Myc target genes.