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Thermo Scientific™ Lab Vision™ c-myc Ab-1, Mouse Monoclonal Antibody


Ensure accurate and reproducible results in immunoprecipitation experiments with Thermo Scientific™ c-myc Ab-1, Mouse Monoclonal Antibody.

Manufacturer: thermo scientific™ lab vision™  MS127P1ABX

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Catalog No. MS127P1ABX

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Description & Specifications

Specifications

Host Species Mouse
Cross Reactivity Chicken
Cross Reactivity Human
Cross Reactivity Mouse
Applications Immunoprecipitation
Clone 9E11; same as A3B2
Quantity 100µL
Regulatory Status RUO
Antigen c-myc Ab-1
Format Concentrated
Immunogen A synthetic peptide, aa 408-439, (AEEQKLISEEDLLRKRREQLKHKLEQLRNSCA) from C-terminus of human c-myc
Isotype IgG2a kappa
Type Primary
Classification Monoclonal
Concentration 1mg/mL
Conjugate Unlabeled
Research Discipline Transcription Regulation

Ensure accurate and reproducible results in immunoprecipitation experiments with Thermo Scientific™ c-myc Ab-1, Mouse Monoclonal Antibody.

c-myc is involved in the control of cell proliferation and differentiation and is amplified and/or overexpressed in a variety of tumors. Translocation of the c-myc locus on chromosome 8 to the immunoglobulin loci on chromosome 14 (heavy chain); 2 (δ light chain); or 22 (light chain) is described in Burkitt's lymphoma and other B-cell lymphoproliferative conditions. An aberrant expression of the c-myc gene occurs in tumors of different origins such as colorectal, gastric, gallbladder, hepatic, mammary, ovarian, endometrial, head and neck, pulmonary, prostatic, thyroidal, oral, ocular, nasopharyngeal, endocrine, as well as hematopoietic neoplasms.

Host Species: Mouse

Clone: 9E11; same as A3B2

Isotype: IgG2a/κ

Species Reactivity: Human, Mouse and Chicken. Others not known.

Epitope: aa 408-439 (Different from Ab-2)

Immunogen: A synthetic peptide, aa 408-439, (AEEQKLISEEDLLRKRREQLKHKLEQLRNSCA) from C-terminus of human c-myc

Molecular Weight: 64-67 kDa

Positive Control: Raji cells

Cellular Localization: Nuclear and cytoplasmic

Recommended for:

  • Immunoprecipitation (Native and denatured)
  • Epitope Tagging (Not Suitable)

Note:

USA: RUO; Int'l: RUO