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c-Met (HGF Receptor) Rat anti-Mouse, FITC, Clone: eBioclone 7, eBioscience™

Rat Monoclonal Antibody

$158.05 - $404.55

Specifications

Antigen c-Met (HGF Receptor)
Clone eBioclone 7
Host Species Rat
Gene Alias hepatocyte growth factor receptor
Species Reactivity Mouse
View More Specs

 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

5010050

 
affymetrix
11-8854-80
25μg Each for $158.05

5010051

 
affymetrix
11-8854-82
100μg Each for $404.55
Description & Specifications

Specifications

Antigen c-Met (HGF Receptor)
Clone eBioclone 7
Host Species Rat
Gene Alias hepatocyte growth factor receptor
Species Reactivity Mouse
Applications Flow Cytometry
Regulatory Status RUO
Conjugate FITC
Format Conjugated
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 0.5mg/mL

The eBioclone 7 monoclonal antibody was generated against a mouse c-Met-Ig fusion protein, and reacts with mouse c-Met-transfected cells. Mouse c-Met (HGFR) is a 170kDa receptor tyrosine kinase (RTK) expressed by epithelial cells of the brain, kidney, liver and other tissues. Binding of its ligand, Hepatocyte Growth Factor (HGF), triggers receptor autophosphorylation, and activation of several downstream effectors including the mitogen-activated protein kinases ERK-1 and ERK-2, and PLC gamma. Activation of the c-Met signal transduction pathway leads to mulitple cellular responses including cell motility, scattering, proliferation, survival and angiogenesis. Mutations in human c-Met have been implicated in the development of several malignancies.