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c-Met (HGF Receptor) Rat anti-Human, FITC, Clone: eBioclone 97, eBioscience™

Rat Monoclonal Antibody

$172.55 - $433.55

Specifications

Antigen c-Met (HGF Receptor)
Clone eBioclone 97
Host Species Rat
Gene Alias HGFR, hepatocyte growth factor receptor
Species Reactivity Human
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 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

5010054

 
affymetrix
11885841
25 tests Each for $172.55

501122164

 
affymetrix
11885842
100 tests Each for $433.55
Description & Specifications

Specifications

Antigen c-Met (HGF Receptor)
Clone eBioclone 97
Host Species Rat
Gene Alias HGFR, hepatocyte growth factor receptor
Species Reactivity Human
Applications Flow Cytometry
Regulatory Status RUO
Conjugate FITC
Format Conjugated
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 5μL (1.0μg)/test

The eBioclone 97 monoclonal antibody was generated against a human c-Met-Ig fusion protein, and reacts with human c-Met (HGFR)-transfected cells. Human c-Met is a 145kDa receptor tyrosine kinase (RTK) expressed by epithelial cells of the brain, kidney, liver and other tissues. Binding of its ligand, Hepatocyte Growth Factor (HGF), triggers receptor autophosphorylation, and activation of several downstream effectors including the mitogen-activated protein kinases ERK-1 and ERK-2, and PLC gamma;. Activation of the c-Met signal transduction pathway leads to mulitple cellular responses including cell motility, scattering, proliferation, survival and angiogenesis. Mutations in human c-Met have been implicated in the development of several malignancies.