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c-Maf Mouse anti-Human, Mouse, PE, Clone: sym0F1, eBioscience™

Mouse Monoclonal Antibody

$187.05 - $477.05

Specifications

Antigen c-Maf
Clone sym0F1
Host Species Mouse
Gene Alias Maf
Species Reactivity Human, Mouse
View More Specs

 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

501122476

 
affymetrix
12985542
100 tests Each for $477.05

501122475

 
affymetrix
12985541
25 tests Each for $187.05
Description & Specifications

Specifications

Antigen c-Maf
Clone sym0F1
Host Species Mouse
Gene Alias Maf
Species Reactivity Human, Mouse
Applications Flow Cytometry (Intracellular Staining)
Regulatory Status RUO
Conjugate PE
Format Conjugated
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 5μL (0.06μg)/test

The sym0F1 monoclonal antibody reacts with human and mouse c-Maf, a 42kDa basic leucine zipper transcription factor shown to be involved in the neural, ocular and hematopoietic systems. In hematopoietic cells, it was first shown to be crucial for IL-4 expression in Th2 and was the first transcription factor believed to be Th subset-specific. More recent evidence shows that specific phospho-tyrosine residues lead to upregulation of IL-4. c-Maf has also been shown to be important to differentiation and function in both Th17 and Tfh cells. It drives expression of IL-21 in both cell types, while promoting expression of IL-23R in Th17 and CXCR5 in Tfh as well.

Sym0F1 does not cross-react with MafA or MafB.