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BTK Recombinant Human Protein DFS Item

BTK Recombinant Human Protein

Manufacturer:  Life Technologies LSPV3587

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Catalog No. PV3587



Description

Description

Bruton tyrosine kinase (BTK) is a cytoplasmic tyrosine kinase belonging to the SRC-related TEC subfamily of tyrosine kinases. Mutations in the BTK gene have been linked to severe developmental blocks in human B-cell ontogeny and immunodeficiency disorders.
Specifications

Specifications

NP_000052
Protein assays and analysis
Frozen
BTK Recombinant Human Protein
1mg
For research use only. Not for use in diagnostic procedures
BTK, ATK, XLA
BTK was pre-diluted in enzyme dilution buffer and assayed in 12.5mM Tris (pH 7.5), 10mM MgCl2, 1mM EGTA, 0.5mM Na3VO4, 5mM β-glycerophosphate, 2mM DTT, 0.01% Triton™ X-100, 200μM ATP, 200μg/mL poly [Glu, Tyr] 4:1 substrate and trace [32P]-γ-ATP for 10 minutes at 30°C
Baculovirus
BTK Recombinant Human Protein
Human
0.31mg/mL
Frozen
81.3kDa
70% by SDS-PAGE
–80°C
1 Each
BTK Recombinant Human Protein
Kinase assay
TEC
220nmoles of phosphate transferred to poly [Glu, Tyr] 4:1 substrate per minute per mg of total protein at 30°C. Activity determined at a final protein concentration of 1μg/mL
His Tag
Documents

For Research Use Only. Not for use in diagnostic procedures.