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BRAF Recombinant Human Protein DFS Item

BRAF Recombinant Human Protein

Manufacturer:  Life Technologies LSPV3848

Catalog No. PV3848



Description

Description

BRAF is involved in the transduction of mitogenic signals from the cell membrane to the nucleus. It is activated by somatic point mutation in human cancer, and is thought to play a role in the postsynaptic responses of hippocampal neuron.
Specifications

Specifications

NP_004324.2
Pharma and biopharma, protein assays and analysis, target and lead identification and validation
113.6kDa
60% by SDS-PAGE
–80°C
1 Each
BRAF, BRAF1
BRAF was pre-diluted in enzyme dilution buffer and assayed in 25mM Tris (pH 7.5), 10mM MgCl2, 0.5mM EGTA, 0.5mM Na3VO4, 5mM β-glycerophosphate, 2.5mM DTT, 0.01% Triton™ X-100, 100μM ATP, 200μg/mL MAP2K1, inactive (P3093) and trace [32P]-γ-ATP for 10 minutes at 30°C
Kinase and inhibitors
RAF
67nmoles of phosphate transferred to MAP2K1, inactive (P3093) per minute per mg of total protein at 30°C. Activity determined at a final protein concentration of 2.5μg/mL
GST Tag
0.17mg/mL
2353, 673
BRAF Recombinant Human Protein
10μg
For research use only. Not for use in diagnostic procedures
Serine/threonine kinase
BRAF Recombinant Human Protein
Kinase assay
Baculovirus
BRAF Recombinant Human Protein
Human
Documents

For Research Use Only. Not for use in diagnostic procedures.