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Brachyury Mouse anti-Human, Clone: X1AO2, eBioscience™

Mouse Monoclonal Antibody

$120.12 - $294.36

Specifications

Antigen Brachyury
Clone X1AO2
Host Species Murine
Species Reactivity Human
Applications Immunocytochemistry,Immunohistochemistry,Immunohistochemistry (Formalin/Paraffin),Microscopy,Western Blot
View More Specs

Disclaimers:

For Research Use Only.



Products ${productFamilyLength}
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
501122851 Life Technologies
LS14977080
25μg Each for $120.12
501122852 Life Technologies
LS14977082
100μg Each for $294.36
Specifications

Description

The monoclonal antibody X1AO2 recognizes human Brachyury, a 47kDa protein encoded by the T gene and functioning as a nuclear transcription factor. This transcription factor binds to specific DNA regions near the palindromic sequence TCACACCT (T-site) through a region in its N-terminus, called the T-box. Brachyury functions during embryogenesis to regulate midline development by establishing the anterior/posterior axis through the regulation of genes involved in mesoderm formation and differentiation. Brachyury is the primary mesoderm marker used to distinguish differentiation of embryonic stem cells into a mesenchymal stem cell lineage. Variations in the T gene in humans are associated with neural tube defects and chordomas. Expression of brachyury is also increased in advanced stage lung tumors and tumor cell lines.
Description & Specifications

Specifications

Brachyury
Murine
Immunocytochemistry,Immunohistochemistry,Immunohistochemistry (Formalin/Paraffin),Microscopy,Western Blot
Unlabeled
Store at 2-8°C.
Monoclonal
0.5mg/mL
X1AO2
Human
RUO
Purified
Primary
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer