Please login to your online account to display your discounted pricing

Tocris™ BMS 195614

Selective RARalpha antagonist

$281.46 - $1,188.81

Specifications

Product Type BMS 195614
Inhibitors BMS 195614
Molecular Weight 448.51
Purity >98
View More Specs

 Disclaimers

For Research Use Only

Products
Catalog Number Mfr. No. Quantity Price Quantity    

366010R

 
tocris™
3660/10
10mg Each for $281.46

366050R

 
tocris™
3660/50
50mg Each for $1,188.81
Description & Specifications

Specifications

Product Type BMS 195614
Inhibitors BMS 195614
Molecular Weight 448.51
Purity >98

Neutral retinoic acid receptor (RAR) α-selective antagonist (Ki = 2.5nM). Displays no significant effect on nuclear receptor corepressor (NCoR) binding; moderately decreases SMRT binding to RAR. Antagonizes agonist-induced coactivator (CoA) recruitment.

  • Chemical Name: 4-[[[5,6-Dihydro-5,5-dimethyl-8-(3-quinolinyl)-2-naphthalenyl]carbonyl]amino]benzoic acid
  • Formula: C29H24N2O3
  • CAS Number: 253310-42-8
  • Solubility: Soluble to 25mM in DMSO
  • Purity: >98