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Blood Group H1 (O) Mouse anti-Human, Alexa Fluor 488, Clone: 17-206, eBioscience™

Mouse Monoclonal Antibody

$201.55 - $564.05

Specifications

Antigen Blood Group H1 (O)
Clone 17-206
Host Species Mouse
Species Reactivity Human
Applications Immunocytochemistry
View More Specs

 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

501124651

 
affymetrix
53981080
25μg Each for $201.55

501124652

 
affymetrix
53981082
100μg Each for $564.05
Description & Specifications

Specifications

Antigen Blood Group H1 (O)
Clone 17-206
Host Species Mouse
Species Reactivity Human
Applications Immunocytochemistry
Applications Immunohistochemistry (Formalin/Paraffin)
Applications Immunohistochemistry (Frozen)
Regulatory Status RUO
Conjugate Alexa Fluor 488
Format Conjugated
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 0.5mg/mL

The monoclonal antibody 17-206 recognizes the human blood group antigen H (O) type 1, a subtype primarily found in epithelial and secretory cells. The precursor H antigen is modified by addition of saccharides to carbohydrate chains of proteins and lipids on erythrocytes and epithelial cells. The type, attachment, location, and sequence of saccharides determines the blood group antigen subtype and is mediated by multiple glycosyl transferases. Depending on ABO blood type, the H antigen is converted into either the A antigen, B antigen, both the A and B antigen, or left unconverted (O antigen). Evidence that the blood group antigen H is not expressed in tumor cells and that the level correlates with disease progression suggests that the blood group antigen H may be involved in cell proliferation, cell adhesion, and angiogenesis, although its exact function remains to be determined. The 17-206 antibody does not recognize blood group antigen H (O) type 2.