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Blimp1 Rat anti-Mouse, PE, Clone: 5E7, eBioscience™

Rat Monoclonal Antibody

$196.68 - $487.08

Specifications

Antigen Blimp1
Clone 5.00E+07
Host Species Rat
Gene Alias Prdm1, B lymphocyte induced maturation protein 1
Species Reactivity Mouse
View More Specs

Disclaimers:

For Research Use Only.



Products ${productFamilyLength}
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
501122467 Life Technologies
LS12985080
25μg Each for $196.68
501122468 Life Technologies
LS12985082
100μg Each for $487.08
Specifications

Description

This 5E7 monoclonal antibody recognizes mouse B lymphocyte-induced maturation protein-1 (Blimp-1), which is also known as Prdm1. Blimp-1 is a transcriptional repressor with five zinc finger domains. Blimp-1 is expressed by terminally differentiating B and T cells. Blimp-1 is also expressed by some dendritic cells, and some NK cells. This transcriptional repressor is required for B cell differentiation into plasma cells and serves as a critical antagonist of CD4+ follicular helper T cell differentiation. While Blimp-1 is not required for priming and development of T and B cell effector function, it is critical for effector cell terminal differentiation. Blimp-1 promotes effector molecule secretion while suppressing proliferation. Blimp-1 also acts as a transcriptional antagonist of Bcl-6 and inhibits genes that are related to memory cell differentiation.
Description & Specifications

Specifications

Blimp1
Rat
Mouse
RUO
Conjugated
Primary
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
5.00E+07
Prdm1, B lymphocyte induced maturation protein 1
Flow Cytometry (Intracellular Staining)
PE
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
0.2mg/mL