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Alfa Aesar™ Bestatin

$134.93 - $254.45

Chemical Identifiers

CAS 58970-76-6
Molecular Formula C16H24N2O4
Molecular Weight (g/mol) 308.378
MDL Number MFCD00083262
InChI Key VGGGPCQERPFHOB-RDBSUJKOSA-N
Synonym bestatin, ubenimex, ubenimexum latin, ubenimex inn:jan, bestatin;ubenimex, s-2-2s,3r-3-amino-2-hydroxy-4-phenylbutanamido-4-methylpentanoic acid, ubenimex bestatin, chembl29292, 2s,3r-3-amino-2-hydroxy-4-phenylbutanoyl-l-leucine, 3-r-amino-2-s-hydroxy-4-phenylbutanoyl-s-leucine
PubChem CID 72172
IUPAC Name (2S)-2-[[(2S,3R)-3-amino-2-hydroxy-4-phenylbutanoyl]amino]-4-methylpentanoic acid
SMILES CC(C)CC(C(=O)O)NC(=O)C(C(CC1=CC=CC=C1)N)O
View More Specs

Products 2
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
AAJ61106MC View Documents Alfa Aesar™
J61106MC
100mg Each for $134.93
 
AAJ61106MD View Documents Alfa Aesar™
J61106MD
250mg Each for $254.45
 
Description

Description

Applications
Bestatin can indirectly act on monocytes by inhibiting Aminopeptidase B, which in turn inhibits the catabolism of tuftsin. Bestatin has also been shown to inhibit Leukotriene A4 hydrolase. It can directly stimulate lymphocytes through its fixation on the cell surface. The agent has been used in multiple leukemia studies. Bestatin is an aminopeptidase inhibitor, inhibits enkephalin metabolism and leukotriene A4 hydrolase. Inhibits tumor cell proliferation.

Solubility
Soluble in water (<1 25), DMSO (2 mg/ml), methanol (5 mg/ml), 1eq. NaOH (50 mM), ethanol (<1mg/mL at 25°C), acetic acid, aq. HCl, and alkaline solution. Insoluble in ethyl acetate, benzene, hexane, and chloroform.

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Keep away from strong oxidizing agents.
Specifications

Chemical Identifiers

58970-76-6
308.378
VGGGPCQERPFHOB-RDBSUJKOSA-N
72172
CC(C)CC(C(=O)O)NC(=O)C(C(CC1=CC=CC=C1)N)O
C16H24N2O4
MFCD00083262
bestatin, ubenimex, ubenimexum latin, ubenimex inn:jan, bestatin;ubenimex, s-2-2s,3r-3-amino-2-hydroxy-4-phenylbutanamido-4-methylpentanoic acid, ubenimex bestatin, chembl29292, 2s,3r-3-amino-2-hydroxy-4-phenylbutanoyl-l-leucine, 3-r-amino-2-s-hydroxy-4-phenylbutanoyl-s-leucine
(2S)-2-[[(2S,3R)-3-amino-2-hydroxy-4-phenylbutanoyl]amino]-4-methylpentanoic acid

Specifications

White
100mg
C16H24N2O4
14,9842
VGGGPCQERPFHOB-RDBSUJKOSA-N
(2S)-2-[[(2S,3R)-3-amino-2-hydroxy-4-phenylbutanoyl]amino]-4-methylpentanoic acid
72172
Powder
233°C to 236°C
58970-76-6
MFCD00083262
bestatin, ubenimex, ubenimexum latin, ubenimex inn:jan, bestatin;ubenimex, s-2-2s,3r-3-amino-2-hydroxy-4-phenylbutanamido-4-methylpentanoic acid, ubenimex bestatin, chembl29292, 2s,3r-3-amino-2-hydroxy-4-phenylbutanoyl-l-leucine, 3-r-amino-2-s-hydroxy-4-phenylbutanoyl-s-leucine
CC(C)CC(C(=O)O)NC(=O)C(C(CC1=CC=CC=C1)N)O
308.378
308.37
Bestatin
Safety and Handling

Safety and Handling

RTECSNumber : OH2915000