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Alfa Aesar™ Bestatin

Manufacturer:  Alfa Aesar™ J61106MD

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Catalog No. AAJ61106MD



Description

Description

Applications
Bestatin can indirectly act on monocytes by inhibiting Aminopeptidase B, which in turn inhibits the catabolism of tuftsin. Bestatin has also been shown to inhibit Leukotriene A4 hydrolase. It can directly stimulate lymphocytes through its fixation on the cell surface. The agent has been used in multiple leukemia studies. Bestatin is an aminopeptidase inhibitor, inhibits enkephalin metabolism and leukotriene A4 hydrolase. Inhibits tumor cell proliferation.

Solubility
Soluble in water (<1 25), DMSO (2 mg/ml), methanol (5 mg/ml), 1eq. NaOH (50 mM), ethanol (<1mg/mL at 25°C), acetic acid, aq. HCl, and alkaline solution. Insoluble in ethyl acetate, benzene, hexane, and chloroform.

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Keep away from strong oxidizing agents.
Specifications

Specifications

Bestatin
233°C to 236°C
58970-76-6
MFCD00083262
bestatin, ubenimex, ubenimexum latin, ubenimex inn:jan, bestatin;ubenimex, s-2-2s,3r-3-amino-2-hydroxy-4-phenylbutanamido-4-methylpentanoic acid, ubenimex bestatin, chembl29292, 2s,3r-3-amino-2-hydroxy-4-phenylbutanoyl-l-leucine, 3-r-amino-2-s-hydroxy-4-phenylbutanoyl-s-leucine
CC(C)CC(C(=O)O)NC(=O)C(C(CC1=CC=CC=C1)N)O
308.378
308.37
White
250mg
C16H24N2O4
14,9842
VGGGPCQERPFHOB-RDBSUJKOSA-N
(2S)-2-[[(2S,3R)-3-amino-2-hydroxy-4-phenylbutanoyl]amino]-4-methylpentanoic acid
72172
Powder

Chemical Identifiers

58970-76-6
308.378
VGGGPCQERPFHOB-RDBSUJKOSA-N
72172
CC(C)CC(C(=O)O)NC(=O)C(C(CC1=CC=CC=C1)N)O
C16H24N2O4
MFCD00083262
bestatin, ubenimex, ubenimexum latin, ubenimex inn:jan, bestatin;ubenimex, s-2-2s,3r-3-amino-2-hydroxy-4-phenylbutanamido-4-methylpentanoic acid, ubenimex bestatin, chembl29292, 2s,3r-3-amino-2-hydroxy-4-phenylbutanoyl-l-leucine, 3-r-amino-2-s-hydroxy-4-phenylbutanoyl-s-leucine
(2S)-2-[[(2S,3R)-3-amino-2-hydroxy-4-phenylbutanoyl]amino]-4-methylpentanoic acid
Safety and Handling

Safety and Handling

RTECSNumber : OH2915000

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