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Benzotropine methanesulfonate, Thermo Scientific Chemicals
Muscarinic receptor antagonist
Supplier: Thermo Scientific Chemicals J6195403
Description
Benzotropine methanesulfonate is used to treat the symptoms of Parkinson?s disease and is currently in clincial trials for chronic back pain. It shows anti-muscarinic effects comparable to Atropine, and also demonstrates competitive anti-nicotinic action at the nAChR (nicotinic acetylcholine receptor).
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
SolubilitySoluble in water (81 mg/ml at 25°C), DMSO (50 mg/ml at 25°C), ethanol (81 mg/ml at 25°C), and ether (very slightly).
Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from oxidizing agents. Store at 4°C.
Specifications
| Benzotropine methanesulfonate | |
| 135°C | |
| C22H29NO4S | |
| 1 g | |
| 14,1121 | |
| Soluble in water (81mg/ml at 25°C),DMSO (50mg/ml at 25°C),ethanol (81mg/ml at 25°C),and ether (very slightly). | |
| CS(O)(=O)=O.CN1[C@@H]2CC[C@@H]1CC(C2)OC(C1=CC=CC=C1)C1=CC=CC=C1 | |
| 403.54 | |
| 403.54 |
| 132-17-2 | |
| White | |
| MFCD00074784 | |
| UN2811 | |
| benztropine mesylate, cogentin, benztropine mesilate, benztropine methanesulfonate, unii-wmj8tl7510, benztropine methylsulfonate, benzatropine mesilate, benzatropine mesylate, benzotropine mesylate, cobrentin methanesulfonate | |
| CPFJLLXFNPCTDW-STYNFMPRSA-N | |
| (1R,5R)-3-(diphenylmethoxy)-8-methyl-8-azabicyclo[3.2.1]octane; methanesulfonic acid | |
| 3246155 | |
| Solid |
Chemical Identifiers
| 132-17-2 | |
| 403.54 | |
| CPFJLLXFNPCTDW-STYNFMPRSA-N | |
| 3246155 | |
| CS(O)(=O)=O.CN1[C@@H]2CC[C@@H]1CC(C2)OC(C1=CC=CC=C1)C1=CC=CC=C1 |
| C22H29NO4S | |
| MFCD00074784 | |
| benztropine mesylate, cogentin, benztropine mesilate, benztropine methanesulfonate, unii-wmj8tl7510, benztropine methylsulfonate, benzatropine mesilate, benzatropine mesylate, benzotropine mesylate, cobrentin methanesulfonate | |
| (1R,5R)-3-(diphenylmethoxy)-8-methyl-8-azabicyclo[3.2.1]octane; methanesulfonic acid |
Safety and Handling
GHS H Statement
H301-H311-H331
Toxic if swallowed.
Toxic in contact with skin.
Toxic if inhaled.
P260-P264b-P270-P271-P280-P284-P301+P310-P302+P352-P304+P340-P310-P312-P330-P361-P363-P501c
H301+H311-H330
DOTInformation : Transport Hazard Class: 6.1; Packing Group: III; Proper Shipping Name: TOXIC SOLIDS, ORGANIC, N.O.S.
EINECSNumber : 205-048-8
RTECSNumber : YM3150000
TSCA : No
Recommended Storage : Ambient temperatures
RUO – Research Use Only