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Bcl-6 Rat anti-Mouse, APC, Clone: BCL-DWN, eBioscience™

Rat Monoclonal Antibody

$196.68 - $473.88

Specifications

Antigen Bcl-6
Clone BCL-DWN
Host Species Rat
Applications Flow Cytometry (Intracellular Staining)
Regulatory Status RUO
View More Specs

Disclaimers:

For Research Use Only.



Products ${productFamilyLength}
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
501123132 Life Technologies
LS17545380
25μg Each for $196.68
501123133 Life Technologies
LS17545382
100μg Each for $473.88
Specifications

Description

This BCL-DWN monoclonal antibody reacts with mouse Bcl-6, which is also known as B-cell lymphoma 6. A member of the POZ family of transcriptional repressors, Bcl-6 is expressed most abundantly in germinal center B cells, as well as in differentiating and activated B cells. This 79kDa protein is essential for germinal center B cell proliferation and survival. Moreover, during B cell development, Bcl-6 plays an important role in promoting pre-B cell survival to enable the generation of a diverse B cell repertoire. Moreover, Bcl-6 is expressed constitutively in diffuse large B cell lymphomas (DLBCLs), Burkitt’s lymphoma, and non-Hodgkin’s lymphoma. Reports also suggest expression of Bcl-6 in CD4+ T follicular helper cells and memory T cells. Bcl-6 has been reported to be antagonized by Blimp-1.
Description & Specifications

Specifications

Bcl-6
Rat
RUO
Conjugated
Primary
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
BCL-DWN
Flow Cytometry (Intracellular Staining)
Allophycocyanin
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
0.2mg/mL