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Bcl-6 Mouse anti-Human, PerCP-eFluor 710, Clone: BCL-UP, eBioscience™

Mouse Monoclonal Antibody

$196.68 - $487.08

Specifications

Antigen Bcl-6
Clone BCL-UP
Host Species Murine
Gene Alias B-cell lymphoma 6
Applications Flow Cytometry (Intracellular Staining)
View More Specs

Disclaimers:

For Research Use Only.



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Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
50245946 Life Technologies
LS46988041
25 Tests Each for $196.68
50245947 Life Technologies
LS46988042
100 Tests Each for $487.08
Specifications

Description

The monoclonal antibody BCL-UP recognizes Bcl-6, also known as B-cell lymphoma 6,which is a member of the POZ family of transcriptional repressors. Bcl-6 is expressed most abundantly in germinal center B cells, as well as in differentiating and activated B cells. This 79kDa protein is essential for germinal center B cell proliferation and survival. During B cell development, Bcl-6 plays an important role in promoting pre-B cell survival to enable the generation of a diverse B cell repertoire. Moreover, Bcl-6 is expressed constitutively in diffuse large B cell lymphomas (DLBCLs), Burkitt’s lymphoma, and non-Hodgkin’s lymphoma. Reports also suggest expression of Bcl-6 in CD4+ T follicular helper cells and memory T cells. Bcl-6 has been reported to be antagonized by Blimp-1.
Description & Specifications

Specifications

Bcl-6
Murine
Flow Cytometry (Intracellular Staining)
PerCP-eFluor 710
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
5μL (0.03μg)/test
BCL-UP
B-cell lymphoma 6
RUO
Conjugated
Primary
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer