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Bcl-6 Mouse anti-Human, Mouse, Clone: GI191E, eBioscience™

Mouse Monoclonal Antibody

$143.88 - $328.68

Specifications

Antigen Bcl-6
Clone GI191E
Host Species Murine
Gene Alias B-cell lymphoma 6, Bcl6
Species Reactivity Human, Mouse
View More Specs

Disclaimers:

For Research Use Only.



Products ${productFamilyLength}
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
5013824 Life Technologies
LS14988780
25μg Each for $143.88
5013825 Life Technologies
LS14988782
100μg Each for $328.68
Specifications

Description

This GI191E monoclonal antibody reacts with mouse and human Bcl-6, which is also known as B-cell lymphoma 6. A member of the POZ family of transcriptional repressors, Bcl-6 is expressed most abundantly in germinal center B cells, as well as in differentiating and activated B cells. This 79kDa protein is essential for germinal center B cell proliferation and survival. Moreover, during B cell development, Bcl-6 plays an important role in promoting pre-B cell survival to enable the generation of a diverse B cell repertoire. Moreover, Bcl-6 is expressed constitutively in diffuse large B cell lymphomas (DLBCLs), Burkitt’s lymphoma, and non-Hodgkin’s lymphoma. Reports also suggest expression of Bcl-6 in CD4+ T follicular helper cells and memory T cells. Bcl-6 has been reported to be antagonized by Blimp-1.
Description & Specifications

Specifications

Bcl-6
Murine
Human, Mouse
RUO
Purified
Primary
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
GI191E
B-cell lymphoma 6, Bcl6
Immunohistochemistry (Formalin/Paraffin),Western Blot
Unlabeled
Store at 2-8°C.
Monoclonal
0.5mg/mL