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Bcl-6 Mouse anti-Human, APC, Clone: BCL-UP, eBioscience™

Mouse Monoclonal Antibody

$170.28 - $460.68

Specifications

Antigen Bcl-6
Clone BCL-UP
Host Species Murine
Gene Alias B-cell lymphoma 6
Species Reactivity Human
View More Specs

Disclaimers:

For Research Use Only.



Products ${productFamilyLength}
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
50245706 Life Technologies
LS17988041
25 Tests Each for $170.28
50245707 Life Technologies
LS17988042
100 Tests Each for $460.68
Specifications

Description

The monoclonal antibody BCL-UP recognizes Bcl-6, also known as B-cell lymphoma 6,which is a member of the POZ family of transcriptional repressors. Bcl-6 is expressed most abundantly in germinal center B cells, as well as in differentiating and activated B cells. This 79kDa protein is essential for germinal center B cell proliferation and survival. During B cell development, Bcl-6 plays an important role in promoting pre-B cell survival to enable the generation of a diverse B cell repertoire. Moreover, Bcl-6 is expressed constitutively in diffuse large B cell lymphomas (DLBCLs), Burkitt’s lymphoma, and non-Hodgkin’s lymphoma. Reports also suggest expression of Bcl-6 in CD4+ T follicular helper cells and memory T cells. Bcl-6 has been reported to be antagonized by Blimp-1.
Description & Specifications

Specifications

Bcl-6
Murine
Human
RUO
Conjugated
Primary
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
BCL-UP
B-cell lymphoma 6
Flow Cytometry (Intracellular Staining)
Allophycocyanin
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
5μL (0.125μg)/test