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Basic Cytokeratin Mouse, Clone: AE3, eBioscience™

Mouse Monoclonal Antibody

$170.28 - $394.68

Specifications

Antigen Basic Cytokeratin
Clone AE3
Host Species Murine
Gene Alias keratin
Applications Immunocytochemistry,Immunohistochemistry,Immunohistochemistry (Formalin/Paraffin),Immunohistochemistry (Frozen),Western Blot
View More Specs

Disclaimers:

For Research Use Only.



Products ${productFamilyLength}
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
5013760 Life Technologies
LS14900080
25μg Each for $170.28
5013761 Life Technologies
LS14900082
100μg Each for $394.68
Specifications

Description

The monoclonal antibody AE3 recognizes many members of the basic (Type II) cytokeratin family. Cytokeratins are intermediate filament proteins comprising one component of the cytoskeleton. There are two large families of cytokeratins, acidic and basic, but all contain the same basic domains (i.e. an α-helical core with an N- and C-terminal domain). The proteins are expressed in epithelial cells, but are developmentally regulated. Many tumors also express these cytokeratins, and their expression can help identify the origin of a neoplasm.

The AE3 monoclonal antibody recognizes the 65 to 67 triplet, 64, 59, 58, 56, 54 and 52kD proteins (also known as cytokeratin 1, 2, 3, 4, 5, 6, 7 and 8) in mouse, human, rat, primate (cynomolgus and rhesus), dog, cat, rabbit and chicken.
Description & Specifications

Specifications

Basic Cytokeratin
Murine
Immunocytochemistry,Immunohistochemistry,Immunohistochemistry (Formalin/Paraffin),Immunohistochemistry (Frozen),Western Blot
Unlabeled
Store at 2-8°C.
Monoclonal
0.5mg/mL
AE3
keratin
RUO
Purified
Primary
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer