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Basic Cytokeratin Mouse, Clone: AE3, eBioscience™

Mouse Monoclonal Antibody

$187.05 - $433.55

Specifications

Antigen Basic Cytokeratin
Clone AE3
Host Species Mouse
Gene Alias keratin
Species Reactivity Canine, Chicken, Human, Mouse, Non-human primate, Rabbit, Rhesus Ma
View More Specs

 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

5013760

 
affymetrix
14-9000-80
25μg Each for $187.05

5013761

 
affymetrix
14-9000-82
100μg Each for $433.55
Description & Specifications

Specifications

Antigen Basic Cytokeratin
Clone AE3
Host Species Mouse
Gene Alias keratin
Species Reactivity Canine, Chicken, Human, Mouse, Non-human primate, Rabbit, Rhesus Ma
Applications Immunocytochemistry
Applications Immunohistochemistry
Applications Immunohistochemistry (Formalin/Paraffin)
Applications Immunohistochemistry (Frozen)
Applications Western Blotting
Regulatory Status RUO
Conjugate Unlabeled
Format Purified
Storage Requirements Store at 2-8°C.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 0.5mg/mL

The monoclonal antibody AE3 recognizes many members of the basic (Type II) cytokeratin family. Cytokeratins are intermediate filament proteins comprising one component of the cytoskeleton. There are two large families of cytokeratins, acidic and basic, but all contain the same basic domains (i.e. an α-helical core with an N- and C-terminal domain). The proteins are expressed in epithelial cells, but are developmentally regulated. Many tumors also express these cytokeratins, and their expression can help identify the origin of a neoplasm.

The AE3 monoclonal antibody recognizes the 65 to 67 triplet, 64, 59, 58, 56, 54 and 52kD proteins (also known as cytokeratin 1, 2, 3, 4, 5, 6, 7 and 8) in mouse, human, rat, primate (cynomolgus and rhesus), dog, cat, rabbit and chicken.