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Tocris™ BAN ORL 24

Potent and selective NOP antagonist

$250.62 - $1,052.58

Specifications

Product Type BAN ORL 24
Inhibitors BAN ORL 24
Molecular Weight 506.51
Purity >97
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 Disclaimers

For Research Use Only

Products
Catalog Number Mfr. No. Quantity Price Quantity    

366110R

 
tocris™
3661/10
10mg Each for $250.62

366150R

 
tocris™
3661/50
50mg Each for $1,052.58
Description & Specifications

Specifications

Product Type BAN ORL 24
Inhibitors BAN ORL 24
Molecular Weight 506.51
Purity >97

Potent and selective NOP receptor antagonist (IC50 values are 0.27, 2500, 6700 and > 10000nM for NOP, κ-,μ- and δ-receptors respectively). Inhibits nociceptin-induced stimulation of [35S]-GTPγS binding and Ca2+ mobilization in CHO cells in vitro and antagonizes NOP agonist-induced reduction in locomotor activity in vivo. Brain penetrant.

  • Chemical Name: (2R)-1-(Phenylmethyl)-N-[3-(spiro[isobenzofuran-1(3H),4'-piperidin]-1-yl)propyl-2-pyrrolidinecarboxamide
  • Formula: C27H35N3O2.2HCl
  • CAS Number: 1401463-54-4
  • Solubility: Soluble to 100mM in water and to 100mM in DMSO
  • Purity: >97