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Thermo Scientific™ Lab Vision™ Bak Ab-2, Rabbit Polyclonal Antibody


Obtain accurate, reproducible results in immunohistochemistry and western blotting experiments with Thermo Scientific™ Bak Ab-2, Rabbit Polyclonal Antibody.

Manufacturer: thermo scientific™ lab vision™  RB1520PABX

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Catalog No. RB1520PABX

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Description & Specifications

Specifications

Host Species Rabbit
Regulatory Status RUO
Format Concentrated
Applications Western Blotting
Isotype IgG
Cross Reactivity Hamster
Cross Reactivity Human
Immunogen A synthetic peptide from the N-terminus of human Bak protein
Quantity 1mL
Antigen Bak Ab-2
Research Discipline Apoptosis
Type Primary
Classification Polyclonal
Conjugate Unlabeled
Formulation Ab without BSA/Azide (Frozen)
Purification Method A431 cells, tonsil
Concentration 1mg/mL
Item Description 1mL; 1mg/mL; Purified w/o BSA, azide

Obtain accurate, reproducible results in immunohistochemistry and western blotting experiments with Thermo Scientific™ Bak Ab-2, Rabbit Polyclonal Antibody.

Bak or Bcl-2-homologous antagonist is a member of the Bcl-2 family of holologous proteins which function in the regulation of apoptosis. The Bcl-2 related proteins interact with one another through the formation of homo- and heterodimers. The susceptibility of cells to apoptotic stimuli is thought to be controlled by the relative ratios of the different Bcl-2 family proteins. Bak is a 211 aa protein which has been demonstrated to accelerate the rate of apoptosis in growth factor deprived murine lymphoid, neuronal and fibroblastic cell lines. Bak has been localized by immunohistochemistry to the cytosol of cells and stains in a punctate pattern characteristic of other bcl-2 family proteins, which have been localized to intracellular organelles.

Host Species: Rabbit

Isotype: IgG

Species Reactivity: Human and Mouse. Hamster (Weakly). Others not known.

Epitope: N-terminal

Immunogen: A synthetic peptide from the N-terminus of human Bak protein

Molecular Weight: ∽24kDa

Positive Control: A431 cells, Tonsil

Cellular Localization: Cytoplasmic

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting

Note:

USA: RUO; Int'l: RUO