missing translation for 'onlineSavingsMsg'
Learn More
Please login to your online account to display your discounted pricing

Alfa Aesar™ Bafilomycin A1, 0.1mg/mL in DMSO, sterile-filtered

Manufacturer:  Alfa Aesar™ J67193XF

 View more versions of this product

Catalog No. AAJ67193XF


 

Specifications

Description

Bafilomycin A1, 0.1mg/mL in DMSO, sterile-filtered; Liquid; Alfa Aesar; 1mL; CAS: 88899-55-2

Applications
Bafilomycin A1 is a potent and selective inhibitor of V-ATPase (vacuolar-type H+ ATPase). The compound can inhibit E1E2 ATPases from sarcoplasmic reticulum, Escherichia coli, and ox brain versus F1F0 ATPases found in bacteria and mitochondria. Some of the more bafilomycin A1 affected ATPases include Neurospora and plant vacuoles, as well as chromaffin granules. Additionally, Bafilomycin A1 prevents lysosomal cholesterol trafficking in macrophages and can be used to distinguish different types of ATPases. Research shows that Bafilomycin A1 can inhibit macroautophagy and promote apoptosis in colon cancer cells.

Solubility
Soluble in methanol, ethanol (0.1 mg/ml), DMSO (0.1 mg/ml), acetone, and chloroform. Insoluble in water.

Notes
Research Use only: Not intended for animal or human diagnostic or therapeutic use.
Description & Specifications

Specifications

Bafilomycin A1
88899-55-2
MFCD06795130
0.1mg/mL in DMSO, sterile-filtered
Liquid
1mL

Chemical Identifiers

88899-55-2
MFCD06795130
Bafilomycin A1, 0.1mg/mL in DMSO, sterile-filtered

Safety and Handling

SDS & Safety Documents

GHS H Statement
H227
Combustible liquid.

GHS P Statement
P210-P280-P370+P378a-P403+P235-P501a
Keep away from heat/sparks/open flames/hot surfaces.
- No smoking.
Wear protective gloves/protective clothing/eye protection/face protection.
In case of fire: Use for extinction: CO2, powder or water spray.
Store in a well-ventilated place.
Keep cool.
Dispose of contents/container in accordance with local/regional/national/international regulations.

Warning

RTECSNumber : RN9781000

storageNote1 : -30° to -10°C