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Alfa Aesar™ Bafilomycin A1, 0.1mg/mL in DMSO, sterile-filtered

$240.12 - $240.12

Chemical Identifiers

CAS 88899-55-2
MDL Number MFCD06795130
Chemical Name or Material Bafilomycin A1, 0.1mg/mL in DMSO, sterile-filtered
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Products ${productFamilyLength}
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
AAJ67193XF SDS Alfa Aesar™
J67193XF
1mL Each for $240.12
Specifications

Description

Applications
Bafilomycin A1 is a potent and selective inhibitor of V-ATPase (vacuolar-type H+ ATPase). The compound can inhibit E1E2 ATPases from sarcoplasmic reticulum, Escherichia coli, and ox brain versus F1F0 ATPases found in bacteria and mitochondria. Some of the more bafilomycin A1 affected ATPases include Neurospora and plant vacuoles, as well as chromaffin granules. Additionally, Bafilomycin A1 prevents lysosomal cholesterol trafficking in macrophages and can be used to distinguish different types of ATPases. Research shows that Bafilomycin A1 can inhibit macroautophagy and promote apoptosis in colon cancer cells.

Solubility
Soluble in methanol, ethanol (0.1 mg/ml), DMSO (0.1 mg/ml), acetone, and chloroform. Insoluble in water.

Notes
Research Use only: Not intended for animal or human diagnostic or therapeutic use.
Description & Specifications

Chemical Identifiers

88899-55-2
MFCD06795130
Bafilomycin A1, 0.1mg/mL in DMSO, sterile-filtered

Specifications

88899-55-2
MFCD06795130
Bafilomycin A1, 0.1mg/mL in DMSO, sterile-filtered
Liquid
1mL

Safety and Handling

GHS H Statement
H227
Combustible liquid.

GHS P Statement
P210-P280-P370+P378a-P403+P235-P501a
Keep away from heat/sparks/open flames/hot surfaces.
- No smoking.
Wear protective gloves/protective clothing/eye protection/face protection.
In case of fire: Use for extinction: CO2, powder or water spray.
Store in a well-ventilated place.
Keep cool.
Dispose of contents/container in accordance with local/regional/national/international regulations.

Warning

RTECSNumber : RN9781000

storageNote1 : -30° to -10°C