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Alfa Aesar™ Azelaic acid, tech. 80%

$49.14 - $198.51

Chemical Identifiers

Chemical Name or Material Azelaic acid
CAS 123-99-9
Purity Grade Technical Grade
Molecular Formula HOOC(CH2)7COOH
Formula Weight 188.22g/mol
MDL Number MFCD00004432
Beilstein 1101094
Merck Index 14,905
Synonym Nonanedioic acid
View More Specs
Products
Catalog Number Mfr. No. Quantity Price Quantity    

AAA172710E

 
alfa aesar™
A17271-0E
2500g Each for $198.51

AAA1727136

 
alfa aesar™
A17271-36
500g Each for $49.14
Description & Specifications

Specifications

Melting Point ≈102°C
Boiling Point 286°C (100mmHg)
Quantity 2500g
Flash Point 215°C (419°F)
Chemical Name or Material Azelaic acid
CAS 123-99-9
Purity Grade Technical Grade
Assay 80%
Molecular Formula HOOC(CH2)7COOH
Formula Weight 188.22g/mol
MDL Number MFCD00004432
Beilstein 1101094
Merck Index 14,905
Synonym Nonanedioic acid
RTECS Number CM1980000
TSCA TSCA

Applications
It is applied in organic synthesis, lacquers, polyester adhesives, and urethane elastomers. Azelaic acid directly inhibits kallikrein 5 (KLK5), down regulating expression of KLK5, toll-like receptor 2 (TLR 2), and cathelicidin, and suppresses activity of serine proteases in vitro, in vivo, and in clinical settings. In PUFA-treated fibroblasts, azelaic acid decreases generation of ROS and up regulates expression of antioxidative enzymes, inhibiting cell damage; agonist activity at PPARν is thought to drive these effects. Azelaic acid also inhibits proliferation of melanocytes. This compound displays antiacne and anticancer potential as well, inhibiting the proliferation of cutaneous melanoma due to suppression of mitochondrial oxidoreductive activity and DNA synthesis. It is a component of a number of hair and skin conditioners. Azelaic acid is used to treat mild to moderate acne, both comedonal acne and inflammatory acne. It is used in lubrication and plasticizers.

Notes
Store away from strong oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.