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Alfa Aesar™ Azadibenzocyclooctyne-NHS ester, with 4 carbon linker

Chemical Identifiers

Chemical Name or Material Azadibenzocyclooctyne-NHS ester
Name Note with 4 carbon linker
Formula Weight 402.40g/mol
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Products
Catalog Number Mfr. No. Quantity Price Quantity    

AAJ64128MB

 
alfa aesar™
J64128-MB
25mg CALL N/A N/A
 Please call Customer Service at 1-800-234-7437 or send an email to help@thermofisher.com for assistance.

AAJ64128MC

 
alfa aesar™
J64128-MC
100mg CALL N/A N/A
 Please call Customer Service at 1-800-234-7437 or send an email to help@thermofisher.com for assistance.
Description & Specifications

Specifications

Color Off-white to gray
Quantity 25mg
Sensitivity Moisture Sensitive
Chemical Name or Material Azadibenzocyclooctyne-NHS ester
Name Note with 4 carbon linker
Physical Form Solid
Formula Weight 402.40g/mol
Solubility Information Soluble in DMF, DMSO, THF and DCM
Health Hazard 1 Warning
Health Hazard 2 GHS H Statement
H315-H319-H335
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.
Health Hazard 3 GHS P Statement
P261-P280-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapors/spray.
Wear protective gloves/protective clothing/eye protection/face protection.
IF IN EYES: Rinse cautiously with water for several minutes.
Remove contact lenses, if present and easy to do.
Continue rinsing.
IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing.
Store locked up.
Dispose of contents/container in accordance with local/regional/national/international regulations.
Storage Note 1 -30° to -10°C

Applications
Azadibenzocyclooctyne-NHS ester, with 4 carbon linker is used in various applications like protein-peptide conjugates, antibody-enzyme or antibody-drug conjugates, protein or peptide-oligonucleotide conjugates and surface modification. It is used to introduce cyclooctyne moiety in to biomolecules and amine containing compounds.

Solubility
Soluble in dimethyl formamide, terahydrofuran, dimethyl sulfocide and dichloromethane.

Notes
Moisture and heat sensitive. Store in cool place. Incompatible with strong oxidizng agents.

Safety and Handling

Warning

GHS P Statement
P261-P280-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapors/spray.
Wear protective gloves/protective clothing/eye protection/face protection.
IF IN EYES: Rinse cautiously with water for several minutes.
Remove contact lenses, if present and easy to do.
Continue rinsing.
IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing.
Store locked up.
Dispose of contents/container in accordance with local/regional/national/international regulations.

GHS H Statement
H315-H319-H335
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.

-30° to -10°C