Please login to your online account to display your discounted pricing

Tocris™ AZ 10417808

Selective non-peptide caspase-3 inhibitor

$250.62 - $1,052.58

Specifications

Product Type AZ 10417808
Inhibitors AZ 10417808
Molecular Weight 434.23
Purity >98
View More Specs

 Disclaimers

For Research Use Only

Products
Catalog Number Mfr. No. Quantity Price Quantity    

217210

 
tocris™
2172/10
10mg Each for $250.62

217250

 
tocris™
2172/50
50mg Each for $1,052.58
Description & Specifications

Specifications

Product Type AZ 10417808
Inhibitors AZ 10417808
Molecular Weight 434.23
Purity >98

Selective non-peptide inhibitor of caspase-3 (Ki = 247nM); displays > 40-fold selectivity over caspases 1, 2, 6, 7 and 8 (Ki > 10μM). Completely blocks staurosporine-induced intracellular DEVDase activity in SH-SY5Y cells (IC50 = 14.9μM).

  • Chemical Name: 2-[(3,4-Dichlorophenyl)amino]-1,4-dihydro-6-nitro-4-oxo-N-2-propenyl-8-quinazolinecarboxamide
  • Formula: C18H13Cl2N5O4
  • CAS Number: 331645-84-2
  • Solubility: Soluble to 25mM in DMSO
  • Purity: >98