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AURKC (Aurora C) Recombinant Human Protein DFS Item

AURKC (Aurora C) Protein

Manufacturer:  Life Technologies LSPV3856

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Catalog No. PV3856



Description

Description

AURKC (Aurora C) is a chromosomal passenger protein that forms complexes with AURKB (Aurora B) and inner centromere proteins, playing a role in organizing microtubules in relation to centrosome⁄spindle function during mitosis. It is overexpressed in several cancer cell lines, suggesting an involvement in oncogenic signal transduction.
Specifications

Specifications

AAH75064
Pharma and biopharma, protein assays and analysis, target and lead identification and validation
61.7kDa
80% by SDS-PAGE
–80°C
1 Each
AURKC (Aurora C), Aurora A, STK13
AURKC (aurora C) was pre-diluted in enzyme dilution buffer and assayed in 25mM Tris (pH 7.5), 10mM MgCl2, 0.5mM EGTA, 0.5mM Na3VO4, 5mM β-glycerophosphate, 2.5mM DTT, 0.01% Triton™ X-100, 200μM ATP, 200μg/mL kemptide peptide substrate (LRRASLG) and trace [ 32P]-γ-ATP for 10 minutes at 30°C
Kinase and inhibitors
Aurora
33nmoles of phosphate transferred to Kemptide peptide substrate (LRRASLG) per minute per mg of total protein at 30°C. Activity determined at a final protein concentration of 8.3μg/mL
GST Tag
0.23mg/mL
10488, 6795
AURKC (Aurora C) Recombinant Human Protein
10μg
For research use only. Not for use in diagnostic procedures
Serine/threonine kinase
AURKC (Aurora C) Recombinant Human Protein
Kinase assay
Baculovirus
AURKC (Aurora C) Recombinant Human Protein
Human
Documents

For Research Use Only. Not for use in diagnostic procedures.