missing translation for 'onlineSavingsMsg'
Learn More
Please login to your online account to display your discounted pricing

Tocris™ AS 605240

Potent and selective PI 3-kinase gamma (PI 3-Kgamma) inhibitor

$199.70 - $834.54

Specifications

Product Type AS 605240
Inhibitors AS 605240
Molecular Weight 257.27
Purity >98
View More Specs

Disclaimers:

For Research Use Only



Products ${productFamilyLength}
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
357810R Tocris™
RDS357810
10mg Each for $199.70
357850R Tocris™
RDS357850
50mg Each for $834.54
Specifications

Description

Potent and selective inhibitor of PI 3-kinase γ (PI 3-Kγ) (IC50 = 8nM). Displays 30-fold selectivity over PI 3-Kδ and PI 3-Kβ and 7.5-fold selectivity over PI 3-Kα. Suppresses the progression of joint inflammation and damage in both lymphocyte-independent and lymphocyte-dependent mouse models of rheumatoid arthritis. Orally active and ATP-competitive.
  • Chemical Name: 5-(6-Quinoxalinylmethylene)-2,4-thiazolidine-2,4-dione
  • Formula: C12H7N3O2S
  • CAS Number: 648450-29-7
  • Solubility: Soluble to 1mM in DMSO with gentle warming
  • Purity: >98
Description & Specifications

Specifications

AS 605240
AS 605240
257.27
>98