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Apramycin sulfate, Thermo Scientific Chemicals
Apramycin sulfate, CAS # 65710-07-8, is the salt of apramycin, the bacteriostatic aminoglycoside antibiotic.
$96.74 - $477.25
Chemical Identifiers
| CAS | 65710-07-8 |
|---|---|
| Molecular Formula | C21H43N5O15S |
| Molecular Weight (g/mol) | 637.66 |
| MDL Number | MFCD06200257 |
| InChI Key | WGLYHYWDYPSNPF-RQFIXDHTSA-N |
| Synonym | Nebramycin II |
| PubChem CID | 3081544 |
| IUPAC Name | (2R,3R,4S,5S,6S)-2-{[(2R,3S,4R,4aR,6S,7R,8aS)-7-amino-6-{[(1R,2R,3S,4R,6S)-4,6-diamino-2,3-dihydroxycyclohexyl]oxy}-4-hydroxy-3-(methylamino)-octahydropyrano[3,2-b]pyran-2-yl]oxy}-5-amino-6-(hydroxymethyl)oxane-3,4-diol; sulfuric acid |
| SMILES | OS(O)(=O)=O.CN[C@H]1[C@@H](O)[C@H]2O[C@H](O[C@@H]3[C@@H](N)C[C@@H](N)[C@H](O)[C@H]3O)[C@H](N)C[C@@H]2O[C@@H]1O[C@H]1O[C@H](CO)[C@@H](N)[C@H](O)[C@H]1O |
| Catalog Number | Mfr. No. | Quantity | Price | Quantity | |||||
|---|---|---|---|---|---|---|---|---|---|
| Catalog Number | Mfr. No. | Quantity | Price | Quantity | |||||
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AAJ6661603
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Thermo Scientific Chemicals
J6661603 |
1 g |
Each for $96.74
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AAJ6661609
|
Thermo Scientific Chemicals
J6661609 |
10 g |
Each for $477.25
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Description
Apramycin sulfate binds to the deep groove of RNA and effectively inhibits ribosomal translocation prohibiting protein synthesis.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
General Description
• Apramycin is a 2-deoxysteptamine derivative and an aminoglycoside originally isolated from Streptomyces tenebrarius
• Apramycin sulfate is comprised of a bicyclic sugar moiety and a monosubstituted deoxystreptamine attached to a sulfate group
Application
• Apramycin sulfate exhibits antibiotic activity against gram-negative bacteria
• It is suitable for laboratory use against Escherichia coli, Klebsiella pneumoniae, and Pseudomonas aeruginosa
• It is also used for laboratory study of infectious disease
Chemical Identifiers
| 65710-07-8 | |
| 637.66 | |
| WGLYHYWDYPSNPF-RQFIXDHTSA-N | |
| 3081544 | |
| OS(O)(=O)=O.CN[C@H]1[C@@H](O)[C@H]2O[C@H](O[C@@H]3[C@@H](N)C[C@@H](N)[C@H](O)[C@H]3O)[C@H](N)C[C@@H]2O[C@@H]1O[C@H]1O[C@H](CO)[C@@H](N)[C@H](O)[C@H]1O |
| C21H43N5O15S | |
| MFCD06200257 | |
| Nebramycin II | |
| (2R,3R,4S,5S,6S)-2-{[(2R,3S,4R,4aR,6S,7R,8aS)-7-amino-6-{[(1R,2R,3S,4R,6S)-4,6-diamino-2,3-dihydroxycyclohexyl]oxy}-4-hydroxy-3-(methylamino)-octahydropyrano[3,2-b]pyran-2-yl]oxy}-5-amino-6-(hydroxymethyl)oxane-3,4-diol; sulfuric acid |
Specifications
| Apramycin Sulfate | |
| 65710-07-8 | |
| C21H43N5O15S | |
| Nebramycin II | |
| WGLYHYWDYPSNPF-RQFIXDHTSA-N | |
| (2R,3R,4S,5S,6S)-2-{[(2R,3S,4R,4aR,6S,7R,8aS)-7-amino-6-{[(1R,2R,3S,4R,6S)-4,6-diamino-2,3-dihydroxycyclohexyl]oxy}-4-hydroxy-3-(methylamino)-octahydropyrano[3,2-b]pyran-2-yl]oxy}-5-amino-6-(hydroxymethyl)oxane-3,4-diol; sulfuric acid | |
| 3081544 | |
| Yellow | |
| >110°C (230°F) | |
| Apramycin sulfate |
| Powder | |
| 168°C | |
| MFCD06200257 | |
| Soluble in water at 25mg/ml | |
| OS(O)(=O)=O.CN[C@H]1[C@@H](O)[C@H]2O[C@H](O[C@@H]3[C@@H](N)C[C@@H](N)[C@H](O)[C@H]3O)[C@H](N)C[C@@H]2O[C@@H]1O[C@H]1O[C@H](CO)[C@@H](N)[C@H](O)[C@H]1O | |
| 637.66 | |
| 637.65 | |
| 1 g | |
| 823°C |
Safety and Handling
H360-H315-H319; May damage fertility or the unborn child. Causes skin irritation. Causes serious eye irritation.
P201-P202-P264b-P280i-P281-P302+P352-P305+P351+P338-P308+P313-P332+P313-P362-P501c
H315-H319-H360
EINECSNumber : 265-890-7
TSCA : No
Recommended Storage : Keep cold
RUO – Research Use Only