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Alfa Aesar™ Antibiotic A23187, 98%

An antibiotic and calcium ionophore

$280.66 - $280.66

Chemical Identifiers

CAS 52665-69-7
Molecular Formula C29H37N3O6
Molecular Weight (g/mol) 523.63
MDL Number MFCD00151202
InChI Key HIYAVKIYRIFSCZ-MVEUKLNNSA-N
Synonym Calcimycin; Calcium ionophore A23187
PubChem CID 97043288
IUPAC Name 5-(methylamino)-2-[[(2R,3S,5S,6S,8S,9S)-3,5,9-trimethyl-2-[(2S)-1-oxo-1-(1H-pyrrol-2-yl)propan-2-yl]-1,7-dioxaspiro[5.5]undecan-8-yl]methyl]-1,3-benzoxazole-4-carboxylic acid
SMILES CC1CCC2(C(CC(C(O2)C(C)C(=O)C3=CC=CN3)C)C)OC1CC4=NC5=C(O4)C=CC(=C5C(=O)O)NC
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Products 1
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
AAJ63020MA View Documents Alfa Aesar™
J63020MA
10mg Each for $280.66
 
Description

Description

Applications
A23187 (Mixed Calcium-Magnesium Salt) is used in cell activation experiments when calcium dose-response data are not required. Ca-Mg ratio ~ 1:1. it is widely used as a compound in cell activation. It is used as a highly selective Ca2+ ionophore. it is used in studies of intracellular Ca2+ mediated events. A23187 has been observed to induce cell activation, differentiation or proliferation. In vitro experimentation has shown A23187 to boost ROS generation and platelet fragmentation. A23187 is a widely used ionophore. It has the ability to increase the intracellular concentrations of cations and is widely used to increase the intracellular levels of calcium. Visualization of Synaptic Ca2+ Calmodulin-Dependent Protein Kinase II Activity in Living Neurons.

Solubility
Soluble in DMSO with warming or sonication. Also soluble in ethanol or ethyl acetate

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature: -20°C. Keep away from strong oxidizing agents.
Specifications

Chemical Identifiers

52665-69-7
523.63
HIYAVKIYRIFSCZ-MVEUKLNNSA-N
97043288
CC1CCC2(C(CC(C(O2)C(C)C(=O)C3=CC=CN3)C)C)OC1CC4=NC5=C(O4)C=CC(=C5C(=O)O)NC
C29H37N3O6
MFCD00151202
Calcimycin; Calcium ionophore A23187
5-(methylamino)-2-[[(2R,3S,5S,6S,8S,9S)-3,5,9-trimethyl-2-[(2S)-1-oxo-1-(1H-pyrrol-2-yl)propan-2-yl]-1,7-dioxaspiro[5.5]undecan-8-yl]methyl]-1,3-benzoxazole-4-carboxylic acid

Specifications

52665-69-7
MFCD00151202
14,1639
Soluble in DMSO with warming or sonication; Also soluble in ethanol or ethyl acetate
CC1CCC2(C(CC(C(O2)C(C)C(=O)C3=CC=CN3)C)C)OC1CC4=NC5=C(O4)C=CC(=C5C(=O)O)NC
523.63
523.62
98%
10mg
C29H37N3O6
1096801
Calcimycin; Calcium ionophore A23187
HIYAVKIYRIFSCZ-MVEUKLNNSA-N
5-(methylamino)-2-[[(2R,3S,5S,6S,8S,9S)-3,5,9-trimethyl-2-[(2S)-1-oxo-1-(1H-pyrrol-2-yl)propan-2-yl]-1,7-dioxaspiro[5.5]undecan-8-yl]methyl]-1,3-benzoxazole-4-carboxylic acid
97043288
Powder
White to Yellow
Antibiotic A23187
Safety and Handling

Safety and Handling

GHS H Statement
H302-H315-H319-H335
Harmful if swallowed.
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.

GHS P Statement
P261-P280-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapors/spray.
Wear protective gloves/protective clothing/eye protection/face protection.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing.
Store locked up.
Dispose of contents/container in accordance with local/regional/national/international regulations.

Warning

RTECSNumber : DM4676000

Recommended Storage : 2° to 8°C